Deciphering SARS-CoV-2 virologic and immunologic features

G Lebeau, D Vagner, E Frumence, F Ah-Pine… - International journal of …, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 and its associated
pathology, COVID-19, have been of particular concerns these last months due to the …

The role of interleukin-22 in lung health and its therapeutic potential for COVID-19

S Fang, D Ju, Y Lin, W Chen - Frontiers in immunology, 2022 - frontiersin.org
Although numerous clinical trials have been implemented, an absolutely effective treatment
against coronavirus disease 2019 (COVID-19) is still elusive. Interleukin-22 (IL-22) has …

Inflammatory pathways in COVID‐19: mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

Anakinra for patients with COVID-19: a meta-analysis of non-randomized cohort studies.

L Pasin, G Cavalli, P Navalesi, N Sella… - European journal of …, 2021 - Elsevier
Introduction Severe COVID-19 cases have a detrimental hyper-inflammatory host response
and different cytokine-blocking biologic agents were explored to improve outcomes …

Nailfold capillaroscopy findings in patients with coronavirus disease 2019: Broadening the spectrum of COVID-19 microvascular involvement

G Natalello, G De Luca, L Gigante, C Campochiaro… - Microvascular …, 2021 - Elsevier
Objective Increasing evidence points to endothelial dysfunction as a key pathophysiological
factor in coronavirus disease-2019 (COVID-19). No specific methods have been identified to …

[HTML][HTML] Dynamic changes in serum IL-6, IL-8, and IL-10 are associated with the outcome of patients with severe COVID-19 in ICU

J Li, L Rong, R Cui, J Feng, Y Jin, Y Yu, X Chen, R Xu - 2020 - europepmc.org
Background: Biomarkers that would help prognosticate outcomes and guide treatment of
patients with severe coronavirus disease 2019 (COVID-19) are currently required. We aimed …

Bioactive lipids in COVID-19-further evidence

UN Das - Archives of medical research, 2021 - Elsevier
Previously, I suggested that arachidonic acid (AA, 20: 4 n-6) and similar bioactive lipids
(BALs) inactivate SARS-CoV-2 and thus, may be of benefit in the prevention and treatment …

Neutrophils and COVID-19: Nots, NETs, and knots

C Nathan - Journal of Experimental Medicine, 2020 - rupress.org
Neutrophils and COVID-19: Nots, NETs, and knots | Journal of Experimental Medicine |
Rockefeller University Press Skip to Main Content Advertisement Umbrella Alt Text …

Granulocyte macrophage colony-stimulating factor has come of age: From a vaccine adjuvant to antiviral immunotherapy

M Petrina, J Martin, S Basta - Cytokine & growth factor reviews, 2021 - Elsevier
GM-CSF acts as a pro-inflammatory cytokine and a key growth factor produced by several
immune cells such as macrophages and activated T cells. In this review, we discuss recent …

Specific interleukin-1 inhibitors, specific interleukin-6 inhibitors, and GM-CSF blockades for COVID-19 (at the edge of sepsis): a systematic review

Y Wang, K Zhu, R Dai, R Li, M Li, X Lv… - Frontiers in …, 2022 - frontiersin.org
Sepsis is a syndrome with high mortality, which seriously threatens human health. During
the pandemic of coronavirus disease 2019 (COVID-19), some severe and critically ill COVID …