COVID-19 vaccines: where did we stand at the end of 2023?

K Lundstrom - Viruses, 2024 - mdpi.com
Vaccine development against SARS-CoV-2 has been highly successful in slowing down the
COVID-19 pandemic. A wide spectrum of approaches including vaccines based on whole …

SARS-CoV2 variant-specific replicating RNA vaccines protect from disease following challenge with heterologous variants of concern

DW Hawman, K Meade-White, J Archer, SS Leventhal… - Elife, 2022 - elifesciences.org
Despite mass public health efforts, the SARS-CoV2 pandemic continues as of late 2021 with
resurgent case numbers in many parts of the world. The emergence of SARS-CoV2 variants …

Nanobodies in the limelight: Multifunctional tools in the fight against viruses

A Moliner-Morro, GM McInerney… - Journal of General …, 2022 - microbiologyresearch.org
Antibodies are natural antivirals generated by the vertebrate immune system in response to
viral infection or vaccination. Unsurprisingly, they are also key molecules in the virologist's …

Enhanced immune responses following heterologous vaccination with self-amplifying RNA and mRNA COVID-19 vaccines

T Elliott, HM Cheeseman, AB Evans, S Day… - PLoS …, 2022 - journals.plos.org
The optimal vaccination strategy to boost responses in the context of pre-existing immune
memory to the SARS-CoV-2 spike (S) glycoprotein is an important question for global public …

Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques

R Marlin, V Godot, S Cardinaud, M Galhaut… - Nature …, 2021 - nature.com
Achieving sufficient worldwide vaccination coverage against SARS-CoV-2 will require
additional approaches to currently approved viral vector and mRNA vaccines. Subunit …

An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats

MA Langereis, IC Albulescu, J Stammen-Vogelzangs… - npj Vaccines, 2021 - nature.com
Early in the SARS-CoV-2 pandemic concerns were raised regarding infection of new animal
hosts and the effect on viral epidemiology. Infection of other animals could be detrimental by …

Combination of a Sindbis-SARS-CoV-2 spike vaccine and αOX40 antibody elicits protective immunity against SARS-CoV-2 induced disease and potentiates long-term …

A Scaglione, S Opp, A Hurtado, Z Lin… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 is a major global public
threat. Currently, a worldwide effort has been mounted to generate billions of effective SARS …

Immunogenicity and protective efficacy of a DNA vaccine inducing optimal expression of the SARS-CoV-2 S gene in hACE2 mice

ZX Li, S Feng, H Zhang, XY Zhuang, C Shang… - Archives of …, 2022 - Springer
The wide spread of coronavirus disease 2019 (COVID-19) has significantly threatened
public health. Human herd immunity induced by vaccination is essential to fight the …

Application of DNA Replicons in Gene Therapy and Vaccine Development

K Lundstrom - Pharmaceutics, 2023 - mdpi.com
DNA-based gene therapy and vaccine development has received plenty of attention lately.
DNA replicons based on self-replicating RNA viruses such as alphaviruses and flaviviruses …

Autoimmune response after SARS-CoV-2 infection and SARS-CoV-2 vaccines

A Hromić-Jahjefendić, K Lundstrom, M Adilović… - Autoimmunity …, 2023 - Elsevier
The complicated relationships between autoimmunity, COVID-19, and COVID-19
vaccinations are described, giving insight into their intricacies. Antinuclear antibodies (ANA) …