The characterization of CD8+ T-cell responses in COVID-19
Y Yang, H Miller, MG Byazrova, F Cndotti… - Emerging Microbes & …, 2024 - Taylor & Francis
This review gives an overview of the protective role of CD8+ T cells in SARS-CoV-2
infection. The cross-reactive responses intermediated by CD8+ T cells in unexposed cohorts …
infection. The cross-reactive responses intermediated by CD8+ T cells in unexposed cohorts …
Nirmatrelvir plus ritonavir in COVID-19: a profile of its use
HA Blair - Drugs & Therapy Perspectives, 2023 - Springer
Oral nirmatrelvir plus ritonavir (Paxlovid™) is an effective treatment option for coronavirus
disease 2019 (COVID-19), the illness caused by severe acute respiratory syndrome …
disease 2019 (COVID-19), the illness caused by severe acute respiratory syndrome …
Exploring the reported adverse effects of COVID-19 vaccines among vaccinated Arab populations: a multi-national survey study
SA Amer, A Al-Zahrani, EA Imam, EM Ishteiwy… - Scientific Reports, 2024 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been a major challenge
worldwide for the past years with high morbidity and mortality rates. While vaccination was …
worldwide for the past years with high morbidity and mortality rates. While vaccination was …
Kidney transplant and dialysis patients remain at increased risk for succumbing to COVID-19
A Weiss, R Hendrickx, E Stensgaard, M Jellingsø… - …, 2023 - journals.lww.com
Background. Immunocompromised patients have been at an increased risk of succumbing
to coronavirus disease 2019 (COVID-19) since the beginning of the pandemic. Methods …
to coronavirus disease 2019 (COVID-19) since the beginning of the pandemic. Methods …
Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell immunoprofiling
F Schreibing, MT Hannani, H Kim, JS Nagai… - Frontiers in …, 2022 - frontiersin.org
Introduction SARS-CoV-2 infection results in varying disease severity, ranging from
asymptomatic infection to severe illness. A detailed understanding of the immune response …
asymptomatic infection to severe illness. A detailed understanding of the immune response …
Use of a Preclinical Natural Transmission Model to Study Antiviral Effects of a Carbohydrate-Binding Module Therapy against SARS-CoV-2 in Hamsters
D Knott, R Fell, JA Potter, S Yuille, FJ Salguero… - Viruses, 2023 - mdpi.com
The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV-2) and its
expansion to a worldwide pandemic resulted in efforts to assess and develop interventions …
expansion to a worldwide pandemic resulted in efforts to assess and develop interventions …
Therapeutics Pipeline
L Sauer, A Sato, HD Davies - Pediatric Clinics, 2024 - pediatric.theclinics.com
Children have unique physiologic, developmental, and psychosocial needs and unique
vulnerabilities, making them a challenging population for which to develop therapeutics. 1 …
vulnerabilities, making them a challenging population for which to develop therapeutics. 1 …
Investigating the Return Possibility of Covid-19 Mutated Strains and Role of Vaccination in Present and Future
K Sadegi, D Soofi, H Mirshekarpour… - Journal of …, 2022 - pnrjournal.com
Covid-19 has killed more than 7 million people in the world so far. With general vaccination
in 2021, the severity of deaths decreased significantly, but after 6 months, new types of …
in 2021, the severity of deaths decreased significantly, but after 6 months, new types of …
[PDF][PDF] Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell immunoprofiling
Methods: We combined single-cell RNA and T cell receptor sequencing with CITE-seq
antibodies to characterize the CD8+ T cell response to SARS-CoV-2 infection at high …
antibodies to characterize the CD8+ T cell response to SARS-CoV-2 infection at high …