Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …

Toxoplasmosis caused by the protozoan Toxoplasma gondii is a major public health
problem, infecting one-third of the world human beings, and leads to abortion in domestic …

Vaccines against parasites have lagged centuries behind those against viral and bacterial
infections, despite the devastating morbidity and widespread effects of parasitic diseases …

BACKGROUND & AIMS: Therapy for chronic hepatitis C (CHC) has limited efficacy, adverse
effects, and high costs. Cohort and vaccine-based preclinical studies have indicated the …

The production, manipulation and rescue of a bacterial artificial chromosome clone of
Vaccinia virus (VAC-BAC) in order to expedite construction of expression vectors and …

Attenuated Salmonella Typhi vaccine strains hold great promise as live vectors for
presentation of foreign antigens from unrelated bacterial, viral and parasitic pathogens to the …

The circumsporozoite protein (CSP) of Plasmodium falciparum is a major surface protein,
which forms a dense coat on the sporozoite's surface. Preclinical research on CSP and …

Traditional chemical adjuvants remain a practical means of enhancing the immunogenicity
of vaccines. Nevertheless, it is recognized that increasing the immunogenicity of viral vectors …

Interest is increasing regarding replicating poxvirus as HIV vaccine vector. In China, the
Tiantan Vaccinia Virus (TV) has been used most extensively in the battle of eradicating …

Subunit viral vaccines are typically not as efficient as live attenuated or inactivated vaccines
at inducing protective immune responses. This paper describes an alternative …