Arsenic contamination of groundwater: a review of sources, prevalence, health risks, and strategies for mitigation

S Shankar, U Shanker, Shikha - The scientific world journal, 2014 - Wiley Online Library
Arsenic contamination of groundwater in different parts of the world is an outcome of natural
and/or anthropogenic sources, leading to adverse effects on human health and ecosystem …

[HTML][HTML] Metabolism, toxicity and anticancer activities of arsenic compounds

I Khairul, QQ Wang, YH Jiang, C Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
A variety of studies indicated that inorganic arsenic and its methylated metabolites have
paradoxical effects, namely, carcinogenic and anticancer effects. Epidemiological studies …

Arsenic exposure and toxicology: a historical perspective

MF Hughes, BD Beck, Y Chen, AS Lewis… - Toxicological …, 2011 - academic.oup.com
The metalloid arsenic is a natural environmental contaminant to which humans are routinely
exposed in food, water, air, and soil. Arsenic has a long history of use as a homicidal agent …

Arsenic-induced oxidative stress and its reversibility

SJS Flora - Free Radical Biology and Medicine, 2011 - Elsevier
This review summarizes the literature describing the molecular mechanisms of arsenic-
induced oxidative stress, its relevant biomarkers, and its relation to various diseases …

Arsenic and selenium toxicity and their interactive effects in humans

HJ Sun, B Rathinasabapathi, B Wu, J Luo, LP Pu… - Environment …, 2014 - Elsevier
Abstract Arsenic (As) and selenium (Se) are unusual metalloids as they both induce and
cure cancer. They both cause carcinogenesis, pathology, cytotoxicity, and genotoxicity in …

Anticancer activity of metal complexes: involvement of redox processes

U Jungwirth, CR Kowol, BK Keppler, CG Hartinger… - 2011 - liebertpub.com
Cells require tight regulation of the intracellular redox balance and consequently of reactive
oxygen species for proper redox signaling and maintenance of metal (eg, of iron and …

[HTML][HTML] Arsenic causing gallbladder cancer disease in Bihar

A Kumar, M Ali, V Raj, A Kumari, M Rachamalla… - Scientific reports, 2023 - nature.com
In recent times Gallbladder cancer (GBC) incidences increased many folds in India and are
being reported from arsenic hotspots identified in Bihar. The study aims to establish …

[HTML][HTML] Mechanisms pertaining to arsenic toxicity

AP Singh, RK Goel, T Kaur - Toxicology international, 2011 - ncbi.nlm.nih.gov
Arsenic is an environmental pollutant and its contamination in the drinking water is
considered as a serious worldwide environmental health threat. The chronic arsenic …

[HTML][HTML] Bladder cancer, a review of the environmental risk factors

S Letašiová, A Medveďová, A Šovčíková… - Environmental …, 2012 - Springer
Background Many epidemiological studies and reviews have been performed to identify the
causes of bladder cancer. The aim of this review is to investigate the links between various …

Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide

J Lu, EH Chew, A Holmgren - Proceedings of the national …, 2007 - National Acad Sciences
Arsenic trioxide (ATO) is an effective cancer therapeutic drug for acute promyelocytic
leukemia and has potential anticancer activity against a wide range of solid tumors. ATO …