Chloroquine (CQ) and hydroxychloroquine (HCQ) are the most common drugs used to
relieve acute and chronic inflammatory diseases. In this article, we present a review about …

Malaria affects 200 million people worldwide. Today, the most successful treatments are
artemisinin-based combination therapies (ACT). Resistance has already been described for …

Artemisinin and its derivatives represent the most important and influential class of drugs in
the fight against malaria. Since the discovery of artemisinin in the early 1970s, the global …

A Temporizing Solution to “Artemisinin Resistance” Three-day therapeutic courses are
losing their efficacy against malarial parasites in the Greater Mekong Subregion. But …

Managing multidrug resistant malaria can be problematic if currently available artemisinin-
containing anti-malarial combination treatments are not used appropriately. Here, I debate …

Malaria is the most lethal and debilitating disease caused by the protozoan parasite
Plasmodium worldwide. The most severe forms of disease and the incidence rates of …

A novel series of indole and benzimidazole bichalcophene diamidine derivatives were
prepared to study their antimicrobial activity against the tropical parasites causing African …

One of the fundamental steps toward malaria control is the use of antimalarial drugs. The
success of antimalarial treatment can be affected by the presence of drug-resistant …

The natural phenomenon of drug resistance is a widespread issue that hampers the
performance of drugs in many major clinical indications. Antibacterial and antifungal drugs …

Plasmodium falciparum multidrug resistance protein 1 (PfMDR1), an adenosine
triphosphate (ATP)-binding cassette (ABC) transporter on the digestive vacuole (DV) …