The pipeline for drugs for control and elimination of neglected tropical diseases: 2. Oral anti-infective drugs and drug combinations for off-label use
KM Pfarr, AK Krome, I Al-Obaidi, H Batchelor… - Parasites & …, 2023 - Springer
In its 'Road map for neglected tropical diseases 2021–2030', the World Health Organization
outlined its targets for control and elimination of neglected tropical diseases (NTDs) and …
outlined its targets for control and elimination of neglected tropical diseases (NTDs) and …
From Bench to Bedside: What Do We Know about Imidazothiazole Derivatives So Far?
M Guo, X Yu, YZ Zhu, Y Yu - Molecules, 2023 - mdpi.com
Imidazothiazole derivatives are becoming increasingly important in therapeutic use due to
their outstanding physiological activities. Recently, applying imidazothiazole as the core …
their outstanding physiological activities. Recently, applying imidazothiazole as the core …
Change in thermal stability and molecular structure characteristics of whey protein beta-lactoglobulin upon the interaction with levamisole hydrochloride
The interaction between beta-lactoglobulin (BLG) and anthelmintic compounds including
levamisole (LEV) is a matter of great concern as it not only poses potential health and …
levamisole (LEV) is a matter of great concern as it not only poses potential health and …
Safety and efficacy of levamisole in loiasis: a randomized, placebo-controlled, double-blind clinical trial
JT Campillo, P Bikita, M Hemilembolo… - Clinical Infectious …, 2022 - academic.oup.com
Background Individuals with high microfilarial densities (MFDs) of Loa loa are at risk of
developing serious adverse events (SAEs) after ivermectin treatment. Pretreatment with …
developing serious adverse events (SAEs) after ivermectin treatment. Pretreatment with …
Onchocerca volvulus microfilariae in the anterior chambers of the eye and ocular adverse events after a single dose of 8 mg moxidectin or 150 µg/kg ivermectin …
EM Kanza, A Nyathirombo, JP Larbelee, NO Opoku… - Parasites & …, 2024 - Springer
Background After ivermectin became available, diethylcarbamazine (DEC) use was
discontinued because of severe adverse reactions, including ocular reactions, in individuals …
discontinued because of severe adverse reactions, including ocular reactions, in individuals …
O. volvulus microfilariae in the anterior chambers of the eye and ocular adverse events after a single dose of 8 mg moxidectin or 150 µg/kg ivermectin: Results of a …
EM Kanza, A Nyathirombo, JP Larbelee, NO Opoku… - 2023 - researchsquare.com
Background After ivermectin became available, diethylcarbamazine (DEC) use was
discontinued because of severe adverse reactions, including ocular reactions, in individuals …
discontinued because of severe adverse reactions, including ocular reactions, in individuals …
Acute Toxic Effects of levamisole and Ivermectin in Mice
FF Almawla, BK Al-baggou - Journal of Applied Veterinary …, 2023 - javs.journals.ekb.eg
The study's objectives were to investigate the acute toxicity and related biochemical effects
of levamisole and ivermectin in mice. The 24 h oral median lethal dose (LD50) of levamisole …
of levamisole and ivermectin in mice. The 24 h oral median lethal dose (LD50) of levamisole …
Chronic levamisole exposure in male rats alters sexual behavior and induces apoptosis in the testis
Levamisole is an anti-helminthic drug developed and introduced in veterinary medicine, and
it has been used more frequently after the inclusion of its usage in human medicine …
it has been used more frequently after the inclusion of its usage in human medicine …
Antihelminthic drugs
IJ Onakpoya - Side Effects of Drugs Annual, 2022 - Elsevier
This chapter reviews harms reporting related to antihelminthic drugs published in the
literature between January and December 2021, and includes albendazole …
literature between January and December 2021, and includes albendazole …
Oral Faropenem Sodium—Implications for Antimicrobial Resistance and Treatment Effectiveness
D Dharmapalan, SJ Chandy - Indian pediatrics, 2022 - Springer
Rising antimicrobial resistance (AMR) is causing therapeutic failures with antibiotics.
Inappropriate use is a contributing factor. One such antibiotic on the radar is faropenem, a …
Inappropriate use is a contributing factor. One such antibiotic on the radar is faropenem, a …