Biomarkers of periodontitis and its differential DNA methylation and gene expression in immune cells: a systematic review

AM Cardenas, LJ Ardila, R Vernal… - International Journal of …, 2022 - mdpi.com
The characteristic epigenetic profile of periodontitis found in peripheral leukocytes denotes
its impact on systemic immunity. In fact, this profile not only stands for periodontitis as a low …

Autosomal sex-associated co-methylated regions predict biological sex from DNA methylation

E Gatev, AM Inkster, GL Negri, C Konwar… - Nucleic Acids …, 2021 - academic.oup.com
Sex is a modulator of health that has been historically overlooked in biomedical research.
Recognizing this knowledge gap, funding agencies now mandate the inclusion of sex as a …

Relationship between plasma circulating cell-free DNA concentration and treatment outcomes including prognosis in patients with advanced non-small cell lung …

WW Peng, Y Liu, HH Sha, SD Wen, Y Fang… - BMC Pulmonary …, 2023 - Springer
Background Some research found that elevated plasma cell-free DNA (cfDNA)
concentrations and poor prognosis are associated in non-small cell lung cancer (NSCLC) …

[HTML][HTML] Epigenetic signature of chronic low back pain in human T cells

S Grégoire, D Cheishvili, M Salmon-Divon, S Dymov… - Pain …, 2021 - journals.lww.com
Objective: Determine if chronic low back pain (LBP) is associated with DNA methylation
signatures in human T cells that will reveal novel mechanisms and potential therapeutic …

Mendelian randomization identifies age at menarche as an independent causal effect factor for gestational diabetes mellitus

L Lu, B Wan, M Sun - Diabetes, Obesity and Metabolism, 2023 - Wiley Online Library
Aims The relationship between age at menarche (AAM) and gestational diabetes mellitus
(GDM) risk is still inconclusive. This Mendelian randomization (MR) analysis was used to …

Sex-Based Mechanisms of Cardiac Development and Function: Applications for Induced-Pluripotent Stem Cell Derived-Cardiomyocytes

Y Luo, S Safabakhsh, A Palumbo, C Fiset… - International Journal of …, 2024 - mdpi.com
Males and females exhibit intrinsic differences in the structure and function of the heart,
while the prevalence and severity of cardiovascular disease vary in the two sexes. However …

An epigenome-wide analysis of sex hormone levels and DNA methylation in male blood samples

J Harbs, S Rinaldi, P Keski-Rahkonen, X Liu… - Epigenetics, 2023 - Taylor & Francis
Endogenous sex hormones and DNA methylation both play important roles in various
diseases. However, their interplay is largely unknown. A deeper understanding of their …

[HTML][HTML] Plasma cell-free DNA methylation combined with tumor mutation detection in prognostic prediction of patients with non-small cell lung cancer (NSCLC)

D Guo, L Yang, J Yang, K Shi - Medicine, 2020 - journals.lww.com
Background: Lung Cancer is one of the most common cancers with high degree of
malignancy, is a devastating disease with a poor prognosis worldwide. prognostic prediction …

Distinctions between sex and time in patterns of DNA methylation across puberty

SR Moore, KL Humphreys, NL Colich, EG Davis… - BMC genomics, 2020 - Springer
Background There are significant sex differences in human physiology and disease; the
genomic sources of these differences, however, are not well understood. During puberty, a …

Risk-focused differences in molecular processes implicated in SARS-CoV-2 infection: corollaries in DNA methylation and gene expression

C Konwar, R Asiimwe, AM Inkster, SM Merrill… - Epigenetics & …, 2021 - Springer
Background Understanding the molecular basis of susceptibility factors to the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health imperative. It …