Vascular contributions to cognitive impairment and dementia (VCID) are characterized by
the aging neurovascular unit being confronted with and failing to cope with biological insults …

Background The use of blood biomarkers after mild traumatic brain injury (mTBI) has been
widely studied. We have identified eight unresolved issues related to the use of five …

Vascular disruption has been implicated in coronavirus disease 2019 (COVID-19)
pathogenesis and may predispose to the neurological sequelae associated with long …

The blood-brain barrier (BBB) is a dynamic interface between the peripheral blood supply
and the cerebral parenchyma, controlling the transport of material to and from the brain …

Aging involves a decline in neural function that contributes to cognitive impairment and
disease. However, the mechanisms underlying the transition from a young-and-healthy to …

The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic
encephalopathy, and the relationships between these disorders, are poorly understood. We …

Importance Young contact sport athletes may be at risk for long-term neuropathologic
disorders, including chronic traumatic encephalopathy (CTE). Objective To characterize the …

Traumatic brain injury (TBI) is a risk factor for dementia. Mixed neurodegenerative
pathologies have been described in late survivors of TBI, but the mechanisms driving post …

Whereas the diagnosis of moderate and severe traumatic brain injury (TBI) is readily visible
on current medical imaging paradigms (magnetic resonance imaging [MRI] and computed …

In-vitro metabolite and drug detection rely on designed materials-based analytical platforms,
which are universally used in biomedical research and clinical practice. However, metabolic …