Breakdown of blood brain barrier as a mechanism of post-traumatic epilepsy

A Dadas, D Janigro - Neurobiology of disease, 2019 - Elsevier
Traumatic brain injury (TBI) accounts for approximately 16% of acute symptomatic seizures
which usually occur in the first week after trauma. Children are at higher risk for post …

Effects of sub-concussion on neuropsychological performance and its potential mechanisms: a narrative review

S Rawlings, R Takechi, AP Lavender - Brain Research Bulletin, 2020 - Elsevier
Concussion and mild traumatic brain injury (mTBI) are recognised as serious medical events
that are relatively common in contact sports. Recently, the seemingly non-injurious …

Insulin resistance and blood-brain barrier dysfunction underlie neuroprogression in bipolar disorder

C Calkin, C McClelland, K Cairns, L Kamintsky… - Frontiers in …, 2021 - frontiersin.org
Bipolar disorder (BD) often progresses to a more chronic and treatment resistant
(neuroprogressive) course. Identifying which patients are at risk could allow for early …

Resonance of human brain under head acceleration

K Laksari, LC Wu, M Kurt, C Kuo… - Journal of The …, 2015 - royalsocietypublishing.org
Although safety standards have reduced fatal head trauma due to single severe head
impacts, mild trauma from repeated head exposures may carry risks of long-term chronic …

Concussion susceptibility is mediated by spreading depolarization-induced neurovascular dysfunction

E Parker, R Aboghazleh, G Mumby, R Veksler, J Ofer… - Brain, 2022 - academic.oup.com
The mechanisms underlying the complications of mild traumatic brain injury, including post-
concussion syndrome, post-impact catastrophic death, and delayed neurodegeneration …

Is salivary S100B a biomarker of traumatic brain injury? A pilot study

D Janigro, K Kawata, E Silverman, N Marchi… - Frontiers in …, 2020 - frontiersin.org
Traumatic brain injury (TBI) results in short and long-term disability neurodegeneration. Mild
traumatic brain injury (mTBI) represents up to 85% of head injuries; diagnosis and early …

Targeting the cerebrovascular system: next-generation biomarkers and treatment for mild traumatic brain injury

TL Baker, DV Agoston, RD Brady, B Major… - The …, 2022 - journals.sagepub.com
The diagnosis, prognosis, and treatment of mild traumatic brain injuries (mTBIs), such as
concussions, are significant unmet medical issues. The kinetic forces that occur in mTBI …

Salivary S100 calcium-binding protein beta (S100B) and neurofilament light (NfL) after acute exposure to repeated head impacts in collegiate water polo players

DC Monroe, EA Thomas, NJ Cecchi, DA Granger… - Scientific reports, 2022 - nature.com
Blood-based biomarkers of brain injury may be useful for monitoring brain health in athletes
at risk for concussions. Two putative biomarkers of sport-related concussion, neurofilament …

Permeability of the blood–brain barrier after traumatic brain injury: radiological considerations

M Amoo, PJ O'Halloran, J Henry… - Journal of …, 2022 - liebertpub.com
Traumatic brain injury (TBI) is a leading cause of death and disability, especially in young
persons, and constitutes a major socioeconomic burden worldwide. It is regarded as the …

Repetitive mTBI is associated with age-related reductions in cerebral blood flow but not cortical thickness

AL Clark, AJ Weigand, KJ Bangen… - Journal of Cerebral …, 2021 - journals.sagepub.com
Mild traumatic brain injury (mTBI) is a risk factor for Alzheimer's disease (AD), and evidence
suggests cerebrovascular dysregulation initiates deleterious neurodegenerative cascades …