Mild traumatic brain injury (mTBI) is a risk factor for Alzheimer's disease (AD), and evidence
suggests cerebrovascular dysregulation initiates deleterious neurodegenerative cascades …

Although concussion has been a subject of interest for centuries, this condition remains
poorly understood. The mechanistic underpinnings and accepted definition of concussion …

It is widely accepted that glutamate is the most important excitatory neurotransmitter in the
central nervous system (CNS). However, there is also a large amount of glutamate in the …

Neurological disorders account for a majority of non-malignant disability in humans and are
often associated with dysfunction of the blood–brain barrier (BBB). Recent evidence shows …

Cerebral amyloid angiopathy (CAA) consists of beta-amyloid deposition in the walls of the
cerebrovasculature and is commonly associated with Alzheimer's disease (AD). However …

Objectives To explore the utility of dynamic contrast-enhanced (DCE) MR imaging for
quantitative analysis of blood-brain barrier disruption in mild traumatic brain injury (mTBI) …

Background and Purpose—The diagnosis of transient ischemic attack is challenging.
Evidence of acute ischemia on MRI diffusion-weighted imaging is highly variable and …

Abstract Background and Purpose Dysfunction of the blood–brain-barrier (BBB) is a
recognized pathological consequence of traumatic brain injury (TBI) which may play an …

Background The blood‐brain barrier (BBB), which separates the intravascular and neuropil
compartments, characterizes the vascular bed of the brain and is essential for its proper …

There is common agreement that many disorders of the central nervous system are
'complex', that is, there are many potential factors that influence the development of the …