The role and diagnostic significance of cellular barriers after concussive head trauma

A Dadas, D Janigro - Concussion, 2018 - Taylor & Francis
The onset of concussive head trauma often triggers an intricate sequence of physical
consequences and pathophysiological responses. These sequelae can be acute (ie …

Evidence of early vasogenic edema following minor head impact that can be reduced with a vasopressin V1a receptor antagonist

P Kulkarni, MR Bhosle, S Lu, NS Simon, S Iriah… - Brain research …, 2020 - Elsevier
Background Does minor head impact without signs of structural brain damage cause short-
term changes in vasogenic edema as measured by an increase apparent diffusion …

Quantitative imaging of blood-brain barrier permeability following repetitive mild head impacts

J Leaston, J Qiao, IC Harding, P Kulkarni… - Frontiers in …, 2021 - frontiersin.org
This was an exploratory study designed to evaluate the feasibility of a recently established
imaging modality, quantitative ultrashort time-to-echo contrast enhanced (QUTE-CE), to …

Targeting of nanoparticles to the cerebral vasculature after traumatic brain injury

S Omo-Lamai, J Nong, K Savalia, BJ Kelley, J Wu… - Plos one, 2024 - journals.plos.org
Traumatic brain injury has faced numerous challenges in drug development, primarily due to
the difficulty of effectively delivering drugs to the brain. However, there is a potential solution …

From spreading depolarization to blood–brain barrier dysfunction: navigating traumatic brain injury for novel diagnosis and therapy

G van Hameren, R Aboghazleh, E Parker… - Nature Reviews …, 2024 - nature.com
Considerable strides in medical interventions during the acute phase of traumatic brain
injury (TBI) have brought improved overall survival rates. However, following TBI, people …

Quantitative analysis of magnetic resonance images for characterization of blood‐brain barrier dysfunction in dogs with brain tumors

E Hanael, S Baruch, O Chai, L Lishitsky… - Journal of veterinary …, 2023 - Wiley Online Library
Background Blood‐brain barrier (BBB) permeability can be assessed quantitatively using
advanced imaging analysis. Hypothesis/Objectives Quantification and characterization of …

Chronic traumatic encephalopathy and neuropathological comorbidities

TD Stein, JF Crary - Seminars in neurology, 2020 - thieme-connect.com
With age, the presence of multiple neuropathologies in a single individual becomes
increasingly common. Given that traumatic brain injury and the repetitive head impacts …

[HTML][HTML] Accelerometer-based head impact detection in soccer-where are we?

B Deju, H Afzal, S Basnayat, A Dali, K Scott… - Health Sciences …, 2023 - Elsevier
Traumatic brain injury (TBI) represents a significant burden on individuals, societies, and
healthcare systems as it is associated with long-term neurological and behavioral …

Abnormalities in functional connectivity in collegiate football athletes with and without a concussion history: Implications and role of neuroactive kynurenine pathway …

TB Meier, MA Lancaster, AR Mayer… - Journal of …, 2017 - liebertpub.com
There is a great need to identify potential long-term consequences of contact sport exposure
and to identify molecular pathways that may be associated with these changes. We tested …

Concussion in the UK: a contemporary narrative review

E Toman, S Hodgson, M Riley, R Welbury… - Trauma Surgery & …, 2022 - tsaco.bmj.com
Concussion has been receiving an increasing amount of media exposure following several
high-profile professional sports controversies and multimillion-dollar lawsuits. The potential …