Neuroimaging biomarkers for drug discovery and development in Schizophrenia

KH Preller, J Scholpp, A Wunder, H Rosenbrock - Biological Psychiatry, 2024 - Elsevier
Schizophrenia is a chronic mental illness affecting up to 1% of the population. While
therapies for positive symptoms are available and efficacious, cognitive and negative …

[HTML][HTML] Growing Up Together in Society (GUTS): A team science effort to predict societal trajectories in adolescence and young adulthood

EA Crone, T Bol, BR Braams, M de Rooij… - Developmental cognitive …, 2024 - Elsevier
Our society faces a great diversity of opportunities for youth. The 10-year Growing Up
Together in Society (GUTS) program has the long-term goal to understand which …

[HTML][HTML] Computational limits to the legibility of the imaged human brain

JK Ruffle, RJ Gray, S Mohinta, G Pombo, C Kaul… - NeuroImage, 2024 - Elsevier
Our knowledge of the organisation of the human brain at the population-level is yet to
translate into power to predict functional differences at the individual-level, limiting clinical …

Neuroanatomical, transcriptomic, and molecular correlates of math ability and their prognostic value for predicting learning outcomes

J Liu, K Supekar, D El-Said, C de Los Angeles… - Science …, 2024 - science.org
Foundational mathematical abilities, acquired in early childhood, are essential for success in
our technology-driven society. Yet, the neurobiological mechanisms underlying individual …

[HTML][HTML] Autoimmune-associated epilepsy–a challenging concept

N Melzer, F Rosenow - Seizure: European Journal of Epilepsy, 2024 - Elsevier
Abstract The current International League Against Epilepsy (ILAE) definition and
classification guidelines for the first time introduced the category of immune-mediated focal …

[HTML][HTML] Julearn: an easy-to-use library for leakage-free evaluation and inspection of ML models

S Hamdan, S More, L Sasse, V Komeyer, KR Patil… - Gigabyte, 2024 - ncbi.nlm.nih.gov
The fast-paced development of machine learning (ML) and its increasing adoption in
research challenge researchers without extensive training in ML. In neuroscience, ML can …

TractGeoNet: A geometric deep learning framework for pointwise analysis of tract microstructure to predict language assessment performance

Y Chen, LR Zekelman, C Zhang, T Xue, Y Song… - Medical Image …, 2024 - Elsevier
We propose a geometric deep-learning-based framework, TractGeoNet, for performing
regression using diffusion magnetic resonance imaging (dMRI) tractography and associated …

Prediction of image interpretation cognitive ability under different mental workloads: a task-state fMRI study

B Li, L Tong, C Zhang, P Chen, L Wang… - Cerebral Cortex, 2024 - academic.oup.com
Visual imaging experts play an important role in multiple fields, and studies have shown that
the combination of functional magnetic resonance imaging and machine learning …

Temporal Variability of Brain-Behavior Relationships in Fine-Scale Dynamics of Edge Time Series

SA Cutts, EJ Chumin, RF Betzel, O Sporns - bioRxiv, 2023 - biorxiv.org
Most work on functional connectivity (FC) in neuroimaging data prefers longer scan sessions
or greater subject count to improve reliability of brain-behavior relationships or predictive …

Improving Predictability, Test-Retest Reliability and Generalisability of Brain-Wide Associations for Cognitive Abilities via Multimodal Stacking

A Tetereva, A Knodt, T Melzer, W van der Vliet… - bioRxiv, 2024 - biorxiv.org
Brain-wide association studies (BWASs) have attempted to relate cognitive abilities with
brain phenotypes, but have been challenged by issues such as predictability, test-retest …