Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: considerations during the COVID-19 crisis

M Iddir, A Brito, G Dingeo, SS Fernandez Del Campo… - Nutrients, 2020 - mdpi.com
The coronavirus-disease 2019 (COVID-19) was announced as a global pandemic by the
World Health Organization. Challenges arise concerning how to optimally support the …

[HTML][HTML] The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism

T Kambe, T Tsuji, A Hashimoto… - Physiological …, 2015 - journals.physiology.org
Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Analysis of the role of the Hippo pathway in cancer

Y Han - Journal of translational medicine, 2019 - Springer
Cancer is a serious health issue in the world due to a large body of cancer-related human
deaths, and there is no current treatment available to efficiently treat the disease as the …

[HTML][HTML] Zinc biochemistry: from a single zinc enzyme to a key element of life

W Maret - Advances in nutrition, 2013 - Elsevier
The nutritional essentiality of zinc for the growth of living organisms had been recognized
long before zinc biochemistry began with the discovery of zinc in carbonic anhydrase in …

Zinc and skin disorders

Y Ogawa, M Kinoshita, S Shimada, T Kawamura - Nutrients, 2018 - mdpi.com
The skin is the third most zinc (Zn)-abundant tissue in the body. The skin consists of the
epidermis, dermis, and subcutaneous tissue, and each fraction is composed of various types …

Mechanisms of glutamate transport

RJ Vandenberg, RM Ryan - Physiological reviews, 2013 - journals.physiology.org
l-Glutamate is the predominant excitatory neurotransmitter in the mammalian central
nervous system and plays important roles in a wide variety of brain functions, but it is also a …

MetalPDB in 2018: a database of metal sites in biological macromolecular structures

V Putignano, A Rosato, L Banci… - Nucleic acids …, 2018 - academic.oup.com
Abstract MetalPDB (http://metalweb. cerm. unifi. it/) is a database providing information on
metal-binding sites detected in the three-dimensional (3D) structures of biological …

The mechanical role of metal ions in biogenic protein‐based materials

E Degtyar, MJ Harrington, Y Politi… - Angewandte Chemie …, 2014 - Wiley Online Library
Protein‐metal interactions—traditionally regarded for roles in metabolic processes—are now
known to enhance the performance of certain biogenic materials, influencing properties …

Current understanding of ZIP and ZnT zinc transporters in human health and diseases

T Kambe, A Hashimoto, S Fujimoto - Cellular and molecular life sciences, 2014 - Springer
Abstract Zinc transporters, the Zrt-, Irt-like protein (ZIP) family and the Zn transporter (ZnT)
family transporters, are found in all aspects of life. Increasing evidence has clarified the …

Zinc coordination spheres in protein structures

M Laitaoja, J Valjakka, J Jänis - Inorganic chemistry, 2013 - ACS Publications
Zinc metalloproteins are one of the most abundant and structurally diverse proteins in
nature. In these proteins, the Zn (II) ion possesses a multifunctional role as it stabilizes the …