[HTML][HTML] NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond

Y Zhu, X Chen, X Liu - Frontiers in immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …

[HTML][HTML] Neutrophils and COVID-19: The road so far

LHA Cavalcante-Silva, DCM Carvalho… - International …, 2021 - Elsevier
The SARS-Cov2 infection triggers a multisystem inflammatory disorder, knowing as COVID-
19, a pandemic disease. This disease is characterized by acute respiratory distress …

COVID-19-associated neurological disorders: the potential route of CNS invasion and blood-brain barrier relevance

A Achar, C Ghosh - Cells, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel human
coronavirus that has sparked a global pandemic of the coronavirus disease of 2019 (COVID …

Stem cell therapy for COVID‐19, ARDS and pulmonary fibrosis

Z Li, S Niu, B Guo, T Gao, L Wang, Y Wang… - Cell …, 2020 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an acute respiratory infectious disease
caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). COVID‐19 …

Severe COVID-19 is characterized by an impaired type I interferon response and elevated levels of arginase producing granulocytic myeloid derived suppressor cells

MJ Dean, JB Ochoa, MD Sanchez-Pino… - Frontiers in …, 2021 - frontiersin.org
COVID-19 ranges from asymptomatic in 35% of cases to severe in 20% of patients.
Differences in the type and degree of inflammation appear to determine the severity of the …

[HTML][HTML] Neutrophils and COVID-19: active participants and rational therapeutic targets

J Hazeldine, JM Lord - Frontiers in immunology, 2021 - frontiersin.org
Whilst the majority of individuals infected with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19, experience mild to …

Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies

PM Varghese, AG Tsolaki, H Yasmin, A Shastri… - Immunobiology, 2020 - Elsevier
The current coronavirus pandemic, COVID-19, is the third outbreak of disease caused by the
coronavirus family, after Severe Acute Respiratory Syndrome and Middle East Respiratory …

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

BA Rosa, M Ahmed, DK Singh… - Communications …, 2021 - nature.com
SARS-CoV-2 virus has infected more than 92 million people worldwide resulting in the
Coronavirus disease 2019 (COVID-19). Using a rhesus macaque model of SARS-CoV-2 …

Elastase and exacerbation of neutrophil innate immunity are involved in multi‐visceral manifestations of COVID‐19

JL Guéant, RM Guéant‐Rodriguez, J Fromonot… - Allergy, 2021 - Wiley Online Library
Background Many arguments suggest that neutrophils could play a prominent role in COVID‐
19. However, the role of key components of neutrophil innate immunity in severe forms of …

Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …