Latency and lytic replication in Epstein–Barr virus-associated oncogenesis

C Münz - Nature Reviews Microbiology, 2019 - nature.com
Epstein–Barr virus (EBV) was the first tumour virus identified in humans. The virus is
primarily associated with lymphomas and epithelial cell cancers. These tumours express …

Cancer risk with topical calcineurin inhibitors, pimecrolimus and tacrolimus, for atopic dermatitis: a systematic review and meta-analysis

N Devasenapathy, A Chu, M Wong… - The Lancet Child & …, 2023 - thelancet.com
Background Atopic dermatitis is a prevalent condition in children and can be effectively
managed with medications such as topical calcineurin inhibitors (pimecrolimus or …

A gammaherpesvirus provides protection against allergic asthma by inducing the replacement of resident alveolar macrophages with regulatory monocytes

B Machiels, M Dourcy, X Xiao, J Javaux, C Mesnil… - Nature …, 2017 - nature.com
The hygiene hypothesis postulates that the recent increase in allergic diseases such as
asthma and hay fever observed in Western countries is linked to reduced exposure to …

[HTML][HTML] Plasmodium infection promotes genomic instability and AID-dependent B cell lymphoma

DF Robbiani, S Deroubaix, N Feldhahn, TY Oliveira… - Cell, 2015 - cell.com
Chronic infection with Plasmodium falciparum was epidemiologically associated with
endemic Burkitt's lymphoma, a mature B cell cancer characterized by chromosome …

Co-infections, inflammation and oncogenesis: future directions for EBV research

AB Rickinson - Seminars in cancer biology, 2014 - Elsevier
Epstein–Barr virus (EBV) is aetiologically linked to a wide range of human tumours. Some
arise as accidents of the virus' lifestyle in its natural niche, the B lymphoid system; these …

Novel therapeutics for Epstein–Barr virus

G Andrei, E Trompet, R Snoeck - Molecules, 2019 - mdpi.com
Epstein–Barr virus (EBV) is a human γ-herpesvirus that infects up to 95% of the adult
population. Primary EBV infection usually occurs during childhood and is generally …

To be or not IIb: a multi-step process for Epstein-Barr virus latency establishment and consequences for B cell tumorigenesis

AM Price, MA Luftig - PLoS pathogens, 2015 - journals.plos.org
Epstein-Barr virus (EBV), a γ-herpesvirus, was the first human tumor virus discovered fifty
years ago in endemic Burkitt lymphoma [1]. Surprisingly, EBV was subsequently recognized …

High-throughput RNA sequencing of paraformaldehyde-fixed single cells

HV Phan, M van Gent, N Drayman, A Basu… - Nature …, 2021 - nature.com
Single-cell transcriptomic studies that require intracellular protein staining, rare cell sorting,
or inactivation of infectious pathogens are severely limited. This is because current high …

Persistent KSHV infection increases EBV-associated tumor formation in vivo via enhanced EBV lytic gene expression

D McHugh, N Caduff, MHM Barros, PC Rämer… - Cell host & …, 2017 - cell.com
The human tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcoma-associated
herpesvirus (KSHV) establish persistent infections in B cells. KSHV is linked to primary …

EBV-positive lymphoproliferations of BT-and NK-cell derivation in non-immunocompromised hosts

SD Dojcinov, F Fend, L Quintanilla-Martinez - Pathogens, 2018 - mdpi.com
The contribution of Epstein-Barr virus (EBV) to the development of specific types of benign
lymphoproliferations and malignant lymphomas has been extensively studied since the …