The role of glutathione redox imbalance in autism spectrum disorder: a review
G Bjørklund, AA Tinkov, B Hosnedlová, R Kizek… - Free Radical Biology …, 2020 - Elsevier
The role of glutathione in autism spectrum disorder (ASD) is emerging as a major topic, due
to its role in the maintenance of the intracellular redox balance. Several studies have …
to its role in the maintenance of the intracellular redox balance. Several studies have …
Genetic and epigenetic studies in non‐syndromic oral clefts
The etiology of non‐syndromic oral clefts (NSOFC) is complex with genetics, genomics,
epigenetics, and stochastics factors playing a role. Several approaches have been applied …
epigenetics, and stochastics factors playing a role. Several approaches have been applied …
Ankyrins and neurological disease
SR Stevens, MN Rasband - Current opinion in neurobiology, 2021 - Elsevier
Highlights•Ankyrins link membrane proteins to the cytoskeleton to form and maintain
membrane micro-domains.•Ankyrins cluster and organize protein complexes that modulate …
membrane micro-domains.•Ankyrins cluster and organize protein complexes that modulate …
Recent developments in autism genetic research: A scientometric review from 2018 to 2022
Genetic research in Autism Spectrum Disorder (ASD) has progressed tremendously in
recent decades. Dozens of genetic loci and hundreds of alterations in the genetic sequence …
recent decades. Dozens of genetic loci and hundreds of alterations in the genetic sequence …
Single-cell transcriptome identifies molecular subtype of autism spectrum disorder impacted by de novo loss-of-function variants regulating glial cells
N Nassir, A Bankapur, B Samara, A Ali, A Ahmed… - Human Genomics, 2021 - Springer
Background In recent years, several hundred autism spectrum disorder (ASD) implicated
genes have been discovered impacting a wide range of molecular pathways. However, the …
genes have been discovered impacting a wide range of molecular pathways. However, the …
Experimental models to study autism spectrum disorders: hiPSCs, rodents and zebrafish
Autism Spectrum Disorders (ASD) affect around 1.5% of the global population, which
manifest alterations in communication and socialization, as well as repetitive behaviors or …
manifest alterations in communication and socialization, as well as repetitive behaviors or …
De novo variants are a common cause of genetic hearing loss
Abstract Purpose De novo variants (DNVs) are a well-recognized cause of genetic
disorders. The contribution of DNVs to hearing loss (HL) is poorly characterized. We aimed …
disorders. The contribution of DNVs to hearing loss (HL) is poorly characterized. We aimed …
[HTML][HTML] Dendritic integration dysfunction in neurodevelopmental disorders
Neurodevelopmental disorders (NDDs) that affect cognition, social interaction, and learning,
including autism spectrum disorder (ASD) and intellectual disability (ID), have a strong …
including autism spectrum disorder (ASD) and intellectual disability (ID), have a strong …
Disease similarity network analysis of Autism Spectrum Disorder and comorbid brain disorders
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with heterogeneous
clinical presentation, variable severity, and multiple comorbidities. A complex underlying …
clinical presentation, variable severity, and multiple comorbidities. A complex underlying …
Neurobehavioral changes arising from early life dopamine signaling perturbations
LB Areal, RD Blakely - Neurochemistry international, 2020 - Elsevier
Dopamine (DA) signaling is critical to the modulation of multiple brain functions including
locomotion, reinforcement, attention and cognition. The literature provides strong evidence …
locomotion, reinforcement, attention and cognition. The literature provides strong evidence …