Use of tocilizumab in kidney transplant recipients with COVID‐19

MJ Pérez‐Sáez, M Blasco… - American Journal of …, 2020 - Wiley Online Library
Acute respiratory distress syndrome associated with coronavirus infection is related to a
cytokine storm with large interleukin‐6 (IL‐6) release. The IL‐6‐receptor blocker tocilizumab …

COVID-19-associated cytokine storm syndrome and diagnostic principles: an old and new Issue

X Yongzhi - Emerging microbes & infections, 2021 - Taylor & Francis
ABSTRACT SARS-CoV-2 has claimed 2,137,908 lives in more than a year. Some COVID-19
patients experience sudden and rapid deterioration with the onset of fatal cytokine storm …

Influenza infection, SARS, MERS and COVID-19: cytokine storm–the common denominator and the lessons to be learned

VA Ryabkova, LP Churilov, Y Shoenfeld - Clinical Immunology, 2021 - Elsevier
The outbreak of COVID-19 reminds us that the emerging and reemerging respiratory virus
infections pose a continuing threat to human life. Cytokine storm syndromes of viral origin …

Prevalence and outcome of dysnatremia in patients with COVID-19 compared to controls

C Atila, CO Sailer, S Bassetti… - European Journal of …, 2021 - academic.oup.com
Objective The pandemic of coronavirus disease (COVID-19) has rapidly spread globally and
infected millions of people. The prevalence and prognostic impact of dysnatremia in COVID …

Ferritin as prognostic marker in COVID-19: the FerVid study

O Para, L Caruso, G Pestelli, F Tangianu… - Postgraduate …, 2022 - Taylor & Francis
Background In COVID-19 patients the progressive clinical deterioration seems secondary to
the activation of a cytokine storm. Ferritin is considered a direct mediator of the immune …

[HTML][HTML] Antiviral phytocompounds “ellagic acid” and “(+)-sesamin” of Bridelia retusa identified as potential inhibitors of SARS-CoV-2 3CL pro using extensive …

AK Umar, JH Zothantluanga, K Aswin, S Maulana… - Structural …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected billions and
has killed millions to date. Studies are being carried out to find therapeutic molecules that …

[HTML][HTML] Immunological characteristics in type 2 diabetes mellitus among COVID-19 patients

M Han, K Ma, X Wang, W Yan, H Wang, J You… - Frontiers in …, 2021 - frontiersin.org
Clinical Trial Registration www. ClinicalTrials. gov, identifier: NCT04365634. Context
Diabetes mellitus was associated with increased severity and mortality of disease in COVID …

[PDF][PDF] Mortality in tocilizumab-treated patients with COVID-19: a systematic review and meta-analysis

O Berardicurti, P Ruscitti, F Ursini… - Clin Exp …, 2020 - clinexprheumatol.org
Objective. People who are exposed to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) could develop a potentially fatal disease with lung involvement and severe …

[HTML][HTML] Interleukin-17A (IL-17A): A silent amplifier of COVID-19

F Maione, GM Casillo, F Raucci, C Salvatore… - Biomedicine & …, 2021 - Elsevier
One of the hallmarks of COVID-19 is the cytokine storm that provokes primarily pneumonia
followed by systemic inflammation. Emerging evidence has identified a potential link …

Expanding the spectrum of the hyperferritinemic syndrome, from pathogenic mechanisms to clinical observations, and therapeutic implications

P Ruscitti, I Di Cola, C Di Muzio, N Italiano, F Ursini… - Autoimmunity …, 2022 - Elsevier
From the introduction of hyperferritinemic syndrome concept, a growing body of evidence
has suggested the role of ferritin as a pathogenic mediator and a relevant clinical feature in …