DNA helicase RECQ1 (also known as RECQL or RECQL1) is a candidate breast cancer
susceptibility gene significantly correlated with clinical outcomes of sporadic breast cancer …

The pig is an excellent animal model for simulating human physiology and a major animal
for meat production and xenotransplantation. Therefore, researching porcine embryonic …

The advancement in high-throughput sequencing (HTS) technology has revolutionized the
field of biology, including genomics, epigenomics, transcriptomics, and metagenomics. This …

Enhancers are genomic elements that regulate gene expression through a variety of
mechanisms. In neuronal systems, enhancer-promoter interactions regulate cell-and tissue …

The process of gene regulation extends as a network in which both genetic sequences and
proteins are involved. The levels of regulation and the mechanisms involved are multiple …

Several methods have been developed to map protein–DNA interactions genome-wide in
the last decades. Protein A-DamID (pA-DamID) is a recent addition to this list with distinct …

DamID maps protein-genome interactions using DNA adenine methyltransferase tethered to
individual chromatin proteins. In a recent issue of Molecluar Cell, Rang et al. introduce …

Multi-omics measurements (bulk and single-cell) are essential to depict the cellular states
comprehensively and thus could derive a deep understanding of underlying mechanisms for …

Although scientists recognize the role of epigenetic mechanisms in DNA damage response,
the complex, mechanistic interplay between chromatin regulation and DNA repair is still …

Tumor suppressor genes (TSGs) are essential for normal cellular function in multicellular
organisms, but many TSGs and tumor-suppressing mechanisms remain unknown. Planarian …