The computational and neural bases of context-dependent learning

JB Heald, DM Wolpert, M Lengyel - Annual Review of …, 2023 - annualreviews.org
Flexible behavior requires the creation, updating, and expression of memories to depend on
context. While the neural underpinnings of each of these processes have been intensively …

Neural algorithms and circuits for motor planning

HK Inagaki, S Chen, K Daie… - Annual review of …, 2022 - annualreviews.org
The brain plans and executes volitional movements. The underlying patterns of neural
population activity have been explored in the context of movements of the eyes, limbs …

[HTML][HTML] Thalamus-driven functional populations in frontal cortex support decision-making

W Yang, SL Tipparaju, G Chen, N Li - Nature neuroscience, 2022 - nature.com
Neurons in frontal cortex exhibit diverse selectivity representing sensory, motor and
cognitive variables during decision-making. The neural circuit basis for this complex …

Cortical feedback loops bind distributed representations of working memory

I Voitov, TD Mrsic-Flogel - Nature, 2022 - nature.com
Working memory—the brain's ability to internalize information and use it flexibly to guide
behaviour—is an essential component of cognition. Although activity related to working …

Machine learning for neural decoding

JI Glaser, AS Benjamin, RH Chowdhury, MG Perich… - Eneuro, 2020 - eneuro.org
Despite rapid advances in machine learning tools, the majority of neural decoding
approaches still use traditional methods. Modern machine learning tools, which are versatile …

Attractor dynamics gate cortical information flow during decision-making

A Finkelstein, L Fontolan, MN Economo, N Li… - Nature …, 2021 - nature.com
Decisions are held in memory until enacted, which makes them potentially vulnerable to
distracting sensory input. Gating of information flow from sensory to motor areas could …

Neural mechanisms that make perceptual decisions flexible

G Okazawa, R Kiani - Annual review of physiology, 2023 - annualreviews.org
Neural mechanisms of perceptual decision making have been extensively studied in
experimental settings that mimic stable environments with repeating stimuli, fixed rules, and …

Pyramidal cell types drive functionally distinct cortical activity patterns during decision-making

S Musall, XR Sun, H Mohan, X An, S Gluf, SJ Li… - Nature …, 2023 - nature.com
Understanding how cortical circuits generate complex behavior requires investigating the
cell types that comprise them. Functional differences across pyramidal neuron (PyN) types …

[HTML][HTML] Modularity and robustness of frontal cortical networks

G Chen, B Kang, J Lindsey, S Druckmann, N Li - Cell, 2021 - cell.com
Neural activity underlying short-term memory is maintained by interconnected networks of
brain regions. It remains unknown how brain regions interact to maintain persistent activity …

Neural activity in the mouse claustrum in a cross-modal sensory selection task

M Chevée, EA Finkel, SJ Kim, DH O'Connor, SP Brown - Neuron, 2022 - cell.com
The claustrum, a subcortical nucleus forming extensive connections with the neocortex, has
been implicated in sensory selection. Sensory-evoked claustrum activity is thought to …