[HTML][HTML] Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
Microbe–host communication is essential to maintain vital functions of a healthy host, and its
disruption has been associated with several diseases, including Crohn's disease and …

Recent advances in the treatment of IBD: Targets, mechanisms and related therapies

J Liu, B Di, L Xu - Cytokine & Growth Factor Reviews, 2023 - Elsevier
Inflammatory bowel disease (IBD), as a representative inflammatory disease, currently has
multiple effective treatment options available and new therapeutic strategies are being …

Versatility of bacterial outer membrane vesicles in regulating intestinal homeostasis

X Wang, S Lin, L Wang, Z Cao, M Zhang, Y Zhang… - Science …, 2023 - science.org
Outer membrane vesicles (OMVs) play vital roles in bacterial communication both
intraspecifically and interspecifically. However, extracellular mechanisms of gut microbiota …

[HTML][HTML] Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer

W Fong, Q Li, J Yu - Oncogene, 2020 - nature.com
Research about the role of gut microbiome in colorectal cancer (CRC) is a newly emerging
field of study. Gut microbiota modulation, with the aim to reverse established microbial …

Microbiota metabolite butyrate constrains neutrophil functions and ameliorates mucosal inflammation in inflammatory bowel disease

G Li, J Lin, C Zhang, H Gao, H Lu, X Gao, R Zhu… - Gut …, 2021 - Taylor & Francis
Host-microbial cross-talk plays a crucial role in maintenance of gut homeostasis. However,
how microbiota-derived metabolites, eg, butyrate, regulate functions of neutrophils in the …

[HTML][HTML] Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis

J Wu, Z Wei, P Cheng, C Qian, F Xu, Y Yang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Background: Gut microbiota, which plays a crucial role in inflammatory bowel diseases
(IBD), might have therapeutic benefits for ulcerative colitis or Crohn's disease. Targeting gut …

Culturing the human microbiota and culturomics

JC Lagier, G Dubourg, M Million, F Cadoret… - Nature Reviews …, 2018 - nature.com
The gut microbiota has an important role in the maintenance of human health and in disease
pathogenesis. This importance was realized through the advent of omics technologies and …

[HTML][HTML] The human gut microbiota: a key mediator of osteoporosis and osteogenesis

KD Seely, CA Kotelko, H Douglas, B Bealer… - International journal of …, 2021 - mdpi.com
An expanding body of research asserts that the gut microbiota has a role in bone
metabolism and the pathogenesis of osteoporosis. This review considers the human gut …

Chronic exposure to polyvinyl chloride microplastics induces liver injury and gut microbiota dysbiosis based on the integration of liver transcriptome profiles and full …

X Chen, J Zhuang, Q Chen, L Xu, X Yue… - Science of the Total …, 2022 - Elsevier
Microplastics (MPs) have become harmful environmental pollutants, and their potential
toxicity to organisms has attracted extensive attention. However, the effects of polyvinyl …

[HTML][HTML] Bile acid–gut microbiota axis in inflammatory bowel disease: from bench to bedside

M Yang, Y Gu, L Li, T Liu, X Song, Y Sun, X Cao… - Nutrients, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder of the
gastrointestinal tract, with increasing prevalence, and its pathogenesis remains unclear …