Clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas)
proteins have transformed genome editing. CRISPR-Cas systems surpass previous genome …

[ES] CRISPR/Cas son una tecnología de edición genética que permite editar y alterar el
ADN de forma precisa y eficiente. Se descubrió por primera vez en E. coli. Está compuesto …

HIV viremia can be controlled by chronic antiretroviral therapy. As a potentially single-shot
alternative, B cells engineered by CRISPR/Cas9 to express anti-HIV broadly neutralizing …

This chapter provides an analysis of global trends in genomic vaccines, a radical innovation
breakthrough (RIB), from technological foresight and pandemic preparedness perspectives …

Effective vaccines inducing lifelong protection against many important infections such as
respiratory syncytial virus (RSV), human immunodeficiency virus (HIV), influenza and …

Although the immune system is well known as the guardian of the human body, certain
infections and cancers can overwhelm its protective barriers. Over the past decade …

Les anticorps (ou immunoglobulines, Ig) produits par les lymphocytes B sont essentiels aux
réponses immunitaires induites par les infections et les vaccins. Les anticorps sont des …

The study of antigen-specific lymphocytes has been a key advancement in immunology over
the past few decades. One innovation allowing for this type of research was the …

Transplantation of B cells engineered ex vivo to secrete broadly neutralizing antibodies
(bNAbs) has shown efficacy in disease models. However, clinical translation of this …

The major histocompatibility complex (MHC) presents peptide antigens to T cells by
engaging with their T cell receptors (TCR). Peptide antigens inducing T cell activation are …