Potential clinical utility of liquid biopsies in ovarian cancer

JW Zhu, P Charkhchi, MR Akbari - Molecular cancer, 2022 - Springer
Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …

Long non-coding RNA NEAT1: a novel target for diagnosis and therapy in human tumors

P Dong, Y Xiong, J Yue, SJB Hanley… - Frontiers in …, 2018 - frontiersin.org
The nuclear paraspeckle assembly transcript 1 (NEAT1, a long non-coding RNA) is
frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with …

[HTML][HTML] LncRNA HOTAIR is a prognostic biomarker for the proliferation and chemoresistance of colorectal cancer via MiR-203a-3p-mediated Wnt/ss-catenin signaling …

Z Xiao, Z Qu, Z Chen, Z Fang, K Zhou… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: HOX transcript antisense RNA (HOTAIR) plays a vital role in
carcinogenesis. However, its functional and regulatory roles remain unclear. In this study …

[HTML][HTML] LncRNA HOTAIR regulates CCND1 and CCND2 expression by sponging miR-206 in ovarian cancer

L Chang, R Guo, Z Yuan, H Shi, D Zhang - Cellular Physiology and …, 2018 - karger.com
Background/Aims: The long noncoding RNA homeobox (HOX) transcript antisense
intergenic RNA (HOTAIR) has been demonstrated to be a vital modulator in the proliferation …

LncRNAs in ovarian cancer

J Wang, A Lu, L Chen - Clinica Chimica Acta, 2019 - Elsevier
Ovarian cancer is one of the most common gynecologic malignancies and has a poor
prognosis. Recently, long noncoding RNAs (lncRNAs) have been identified as key …

Exploring lncRNA-mediated regulatory networks in endometrial cancer cells and the tumor microenvironment: advances and challenges

P Dong, Y Xiong, J Yue, S JB Hanley, N Kobayashi… - Cancers, 2019 - mdpi.com
Recent studies have revealed both the promise and challenges of targeting long non-coding
RNAs (lncRNAs) to diagnose and treat endometrial cancer (EC). LncRNAs are upregulated …

LncRNA LINC00319 accelerates ovarian cancer progression through miR-423-5p/NACC1 pathway

W Du, Z Feng, Q Sun - Biochemical and biophysical research …, 2018 - Elsevier
Abstract Long noncoding RNA (lncRNA) LINC00319 has been reported to promote
carcinogenesis of lung cancer and cutaneous squamous cell carcinoma. However, the role …

miR‐211 sponges lncRNA MALAT1 to suppress tumor growth and progression through inhibiting PHF19 in ovarian carcinoma

F Tao, X Tian, S Ruan, M Shen, Z Zhang - The FASEB Journal, 2018 - Wiley Online Library
Accumulating evidence has indicated that microRNAs (miRNAs) play an important role in
the occurrence and progression of ovarian cancer (OC). However, the function of miRNAs …

[HTML][HTML] Long noncoding RNA FOXD2-AS1 accelerates the gemcitabine-resistance of bladder cancer by sponging miR-143

Q An, L Zhou, N Xu - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Increasing evidences have proved that long noncoding RNAs (lncRNAs) modulate the
tumorigenesis of bladder cancer involved in multiple pathophysiological processes. In the …

[HTML][HTML] The functions and oncogenic roles of CCAT1 in human cancer

Z Liu, QJ Chen, SS Hann - Biomedicine & Pharmacotherapy, 2019 - Elsevier
In various human cancers, long non-coding RNAs (lncRNAs), a novel class of RNAs longer
than 200 nucleotides without protein-coding potential, are implicated in a variety of …