Effects of statins on mitochondrial pathways

H Mollazadeh, E Tavana, G Fanni, S Bo… - Journal of Cachexia …, 2021 - Wiley Online Library
Statins are a family of drugs that are used for treating hyperlipidaemia with a recognized
capacity to prevent cardiovascular disease events. They inhibit β‐hydroxy β‐methylglutaryl …

Exercise interventions combined with dietary supplements in type 2 diabetes mellitus patients—a systematic review of relevant health outcomes

FM Meuffels, E Isenmann, M Strube, A Lesch… - Frontiers in …, 2022 - frontiersin.org
Introduction Physical training can improve several health variables in patients with type 2
diabetes mellitus (T2DM). A growing body of studies also finds a positive influence of dietary …

Vitamin D deficiency is associated with muscle atrophy and reduced mitochondrial function in patients with chronic low back pain

KP Dzik, W Skrobot, KB Kaczor, DJ Flis… - Oxidative Medicine …, 2019 - Wiley Online Library
Recent studies show that vitamin D deficiency may be responsible for muscle atrophy. The
purpose of this study was to investigate markers of muscle atrophy, signalling proteins, and …

Effect of vitamin D supplementation on body composition and cardiorespiratory fitness in overweight men—a randomized controlled trial

C Karefylakis, S Särnblad, A Ariander, G Ehlersson… - Endocrine, 2018 - Springer
Purpose Several observational studies have shown an association between vitamin D
deficiency and non-skeletal major health issues including impaired cardiorespiratory fitness …

[HTML][HTML] Therapeutic influence of simvastatin on MCF-7 and MDA-MB-231 breast cancer cells via mitochondrial depletion and improvement in chemosensitivity of …

V Tripathi, P Jaiswal, R Verma, K Sahu… - Advances in Cancer …, 2023 - Elsevier
Background Breast cancer is the most commonly diagnosed cancer worldwide with 2.26
million cases in 2020. Cancer heterogeneity is the major challenge before existing …

Vitamin D supplementation rescues simvastatin induced myopathy in mice via improving mitochondrial cristae shape

L Ren, L Xuan, F Han, J Zhang, L Gong, Y Lv… - Toxicology and applied …, 2020 - Elsevier
Statin induced myopathy (SIM) is a main deleterious effect leading to the poor treatment
compliance, while the preventive or therapeutic treatments are absent. Mounting evidences …

The role of vitamin D in cancer cachexia

F Penna, A Camperi, M Muscaritoli… - Current Opinion in …, 2017 - journals.lww.com
Vitamin D supplementation is likely beneficial to reduce or delay aging-related sarcopenia
and osteoporosis, although the available data still put in evidence significant discrepancies …

Effects of vitamin D on drugs: Response and disposal

J Peng, Y Liu, J Xie, G Yang, Z Huang - Nutrition, 2020 - Elsevier
Vitamin D supplementation and vitamin D deficiency are common in clinical experience and
in daily life. Vitamin D not only promotes calcium absorption and immune regulation, but …

Effect of vitamin D supplementation on body composition and physical fitness in healthy adults: a double-blind, randomized controlled trial

X Sun, K Tanisawa, Y Zhang, T Ito, S Oshima… - Annals of Nutrition and …, 2020 - karger.com
Introduction: This study aimed to clarify whether 1 year of vitamin D3 supplementation has a
direct effect on body composition and physical fitness in healthy adults. Methods: Ninety-five …

[HTML][HTML] Association of statins with peak oxygen consumption in 4,941 adults: A cross-sectional study

CE Novaes, E Rondon, CFR Rizzo, MO de Oliveira… - IJC Heart & …, 2024 - Elsevier
Background and aims Cardiovascular disease remains a leading cause of mortality, with
statins widely used to reduce its risk. Despite extensive research, the nuanced impact of …