Human body fluid proteome analysis

S Hu, JA Loo, DT Wong - Proteomics, 2006 - Wiley Online Library
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

Mass spectrometry as a diagnostic and a cancer biomarker discovery tool: opportunities and potential limitations

EP Diamandis - Molecular & Cellular Proteomics, 2004 - ASBMB
Serum proteomic profiling, by using surfaced-enhanced laser desorption/ionization-time-of-
flight mass spectrometry, is one of the most promising new approaches for cancer …

Proteomic patterns: their potential for disease diagnosis

Z Xiao, DR Prieto, TP Conrads, TD Veenstra… - Molecular and cellular …, 2005 - Elsevier
Alterations in proteins abundance, structure, or function, act as useful indicators of
pathological abnormalities prior to development of clinical symptoms and as such are often …

National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for use of tumor markers in clinical practice: quality requirements

CM Sturgeon, BR Hoffman, DW Chan, SL Ch'ng… - 2008 - academic.oup.com
Background: This report presents updated National Academy of Clinical Biochemistry
Laboratory Medicine Practice Guidelines summarizing quality requirements for the use of …

Discovery and validation of urinary biomarkers for prostate cancer

D Theodorescu, E Schiffer, HW Bauer… - PROTEOMICS …, 2008 - Wiley Online Library
Only 30% of patients with elevated serum prostate specific antigen (PSA) levels who
undergo prostate biopsy are diagnosed with prostate cancer (PCa). Novel methods are …

[HTML][HTML] Proteomic analysis for the early detection and rational treatment of cancer—realistic hope?

EM Posadas, F Simpkins, LA Liotta, C MacDonald… - Annals of oncology, 2005 - Elsevier
Proteomics is an emerging field in medical science focused on the library of proteins specific
to a given biosystem, the proteome, and understanding relationships therein. This field …

What does the future hold for clinical microbiology?

D Raoult, PE Fournier, M Drancourt - Nature Reviews Microbiology, 2004 - nature.com
In the past decade, clinical microbiology laboratories have undergone important changes
with the introduction of molecular biology techniques and laboratory automation. In the …

Identification of complement C3a as a candidate biomarker in human chronic hepatitis C and HCV‐related hepatocellular carcinoma using a proteomics approach

IN Lee, CH Chen, JC Sheu, HS Lee, GT Huang… - …, 2006 - Wiley Online Library
Although the significant risk factors for hepatocellular carcinoma (HCC) are well known from
epidemiological studies, diagnosis of this disease at an early stage is difficult, and HCC …

The use of proteomics for the assessment of clinical samples in research

S Aldred, MM Grant, HR Griffiths - Clinical biochemistry, 2004 - Elsevier
Proteomics, the analysis of expressed proteins, has been an important developing area of
research for the past two decades [Anderson, NG, Anderson, NL. Twenty years of two …

Detection of tumor markers with ProteinChip® technology

A Wiesner - Current pharmaceutical biotechnology, 2004 - ingentaconnect.com
The early diagnosis of cancer at a curable stage is crucial for the successful treatment of this
disease. Most of the currently used tumor assays appear too late and rely on single …