Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

Background As common, progressive, and chronic causes of disability and death,
neurodegenerative diseases (NDDs) significantly threaten human health, while no effective …

The rapid progress in the field of stem cell research has laid strong foundations for their use
in regenerative medicine applications of injured or diseased tissues. Growing evidences …

Human dental pulp stem cells (hDPSCs) are some of the most promising stem cell types for
regenerative therapies given their ability to grow in the absence of serum and their realistic …

Huntington's disease (HD) is a neurological disorder characterized by a reduction in
medium-spiny neurons in the brain. Currently, there is no cure for HD and treatment relies …

There has been substantial progress in the development of regenerative medicine strategies
for CNS disorders over the last decade, with progression to early clinical studies for some …

Huntington's disease (HD) is one of neurodegenerative diseases, and is defined as a
monogenetic disease due to the mutation of Huntingtin gene. This disease affects several …

Spinocerebellar ataxias are heritable neurodegenerative diseases caused by a cytosine-
adenine-guanine expansion, which encodes a long glutamine tract (polyglutamine) in the …

Huntington's disease (HD), a genetic neurodegenerative disorder, primarily affects the
striatum and cortex with progressive loss of medium-sized spiny neurons (MSNs) and …

Applying stem cell therapy in intractable diseases: a narrative review of decades of progress
and challenges - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …