Abstract MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene
expression by sequential mechanisms such as mRNA breakdown or translational …

Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

Background Kidney injury due to cold storage–associated transplantation (CST) is a major
factor determining the outcome of renal transplant, for which the role and regulation of …

Clear cell renal cell carcinoma (ccRCC) is the most common kidney cancer in the adult
population. Late diagnosis, resistance to therapeutics and recurrence of metastatic lesions …

Renal tubulointerstitial fibrosis (TIF) is considered as the final convergent pathway of
diabetic nephropathy (DN) without effective therapies currently. MiRNAs play a key role in …

The blood microvascular endothelium consists of a heterogeneous population of cells with
regionally distinct morphologies and transcriptional signatures in different tissues and …

Nephrolithiasis is one of the most common and frequent urologic diseases worldwide. The
molecular mechanism of kidney stone formation is complex and remains to be illustrated …

Simple Summary The Wilms tumor is the most common kidney cancer in children. This study
characterized complete miRNA and mRNA profiles using a comprehensive NGS …

Cyclosporine (CsA) is an immunosuppressive agent that often causes acute kidney injury
(AKI) in children. The specific mechanisms underlying CsA-induced AKI are currently …

Diabetic kidney disease (DKD) is a common microvascular complication of diabetes mellitus
(DM). With the increasing prevalence of DM worldwide, the incidence of DKD remains high …