T cells in health and disease

L Sun, Y Su, A Jiao, X Wang, B Zhang - Signal Transduction and …, 2023 - nature.com
T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …

Regulatory T cells (Tregs) and COVID-19: unveiling the mechanisms, and therapeutic potentialities with a special focus on long COVID

M Dhawan, AA Rabaan, S Alwarthan, M Alhajri… - Vaccines, 2023 - mdpi.com
The COVID-19 pandemic has caused havoc all around the world. The causative agent of
COVID-19 is the novel form of the coronavirus (CoV) named SARS-CoV-2, which results in …

SARS-CoV-2 spike-specific regulatory T cells (Treg) expand and develop memory in vaccine recipients suggesting a role for immune regulation in preventing severe …

A Franco, J Song, C Chambers, A Sette, A Grifoni - Autoimmunity, 2023 - Taylor & Francis
We enrolled healthy subjects that received 2 to 4 injections of mRNA-based vaccination to
prevent COVID-19 months to a year from the last vaccine boost, and we found numerous …

The molecular mechanism of actions and clinical utilities of tumor infiltrating lymphocytes in gastrointestinal cancers: a comprehensive review and future prospects …

M Piroozkhah, Y Gholinezhad, M Piroozkhah… - Frontiers in …, 2023 - frontiersin.org
Gastrointestinal (GI) cancers remain a significant global health burden, accounting for a
substantial number of cases and deaths. Regrettably, the inadequacy of dependable …

SARS-CoV-2 Vaccine-induced T-cell response after three doses in people living with HIV on antiretroviral therapy compared to seronegative controls (CTN 328 …

Y Alexandrova, A Yero, RS Mboumba Bouassa… - Viruses, 2023 - mdpi.com
People living with HIV (PLWH) may be at risk for poor immunogenicity to certain vaccines,
including the ability to develop immunological memory. Here, we assessed T-cell …

In-depth analysis of T cell immunity and antibody responses in heterologous prime-boost-boost vaccine regimens against SARS-CoV-2 and Omicron variant

N Heinen, CS Marheinecke, C Bessen… - Frontiers in …, 2022 - frontiersin.org
With the emergence of novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-
CoV-2) Variants of Concern (VOCs), vaccination studies that elucidate the efficiency and …

Regulatory T cells in lung disease and transplantation

P Lao, J Chen, L Tang, J Zhang, Y Chen… - Bioscience …, 2023 - portlandpress.com
Pulmonary disease can refer to the disease of the lung itself or the pulmonary manifestations
of systemic diseases, which are often connected to the malfunction of the immune system …

TREG cells and CXCR3+ circulating TFH cells concordantly shape the neutralizing antibody responses in individuals who have recovered from mild COVID-19

X Zheng, R Lu, D Pan, L Peng, R He… - The Journal of …, 2024 - academic.oup.com
Regulatory T (TREG) cells are involved in the antiviral immune response in patients with
COVID-19; however, whether TREG cells are involved in the neutralizing antibody (nAb) …

T Cell Responses in Pregnant Women Who Received mRNA-Based Vaccination to Prevent COVID-19 Revealed Unknown Exposure to the Natural Infection and …

CD Chambers, J Song, R da Silva Antunes… - International Journal of …, 2024 - mdpi.com
We studied T-cell responses to SARS-CoV-2 in 19 pregnant subjects at different gestational
weeks who received three doses of mRNA-based vaccination to prevent COVID-19. SARS …

Immune-Cell-Based Therapy for COVID-19: Current Status

Y Wang, Q Liang, F Chen, J Zheng, Y Chen, Z Chen… - Viruses, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has become a global pandemic. The interplay between innate …