Senescence is a cellular response to a variety of stress signals that is characterized by a
stable withdrawal from the cell cycle and major changes in cell morphology and physiology …

Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

Infection susceptibility, poor vaccination efficacy, age-related disease onset, and neoplasms
are linked to innate and adaptive immune dysfunction that accompanies aging (known as …

Ovarian fibrosis is a pathological condition associated with aging and is responsible for a
variety of ovarian dysfunctions. Given the known contributions of tissue fibrosis to …

The immune system is the central regulator of tissue homeostasis, ensuring tissue
regeneration and protection against both pathogens and the neoformation of cancer cells. Its …

The senescence‐associated secretory phenotype (SASP), where senescent cells produce a
variety of secreted proteins including inflammatory cytokines, chemokines, matrix …

Cellular senescence is characterized by a tumor-suppressive program as well as a pro-
inflammatory secretome. Neutrophils constitute significant compositions of malignancies and …

In late 2019, an outbreak of coronavirus disease 2019 (COVID‐19) arose, caused by severe
acute respiratory syndrome coronavirus type 2 (SARS‐CoV‐2). This disease rapidly became …