The intestine is a complex organ that promotes digestion, extracts nutrients, participates in
immune surveillance, maintains critical symbiotic relationships with microbiota and affects …

Although single-cell and spatial sequencing methods enable simultaneous measurement of
more than one biological modality, no technology can capture all modalities within the same …

Integrating single-cell multi-omics data is a challenging task that has led to new insights into
complex cellular systems. Various computational methods have been proposed to effectively …

Tissue imaging has become much more colourful in the past decade. Advances in both
experimental and analytical methods now make it possible to image protein markers in …

Metabolic reprogramming in cancer and immune cells occurs to support their increasing
energy needs in biological tissues. Here we propose Single Cell Spatially resolved …

Chemical genetic screens are a powerful tool for exploring how cancer cells' response to
drugs is shaped by their mutations, yet they lack a molecular view of the contribution of …

As patient-tailored therapies are becoming routine, improved methods for comprehensive
profiling of responses at the single-cell level are required. Flow cytometry (FCM) is a …

PANINI: Combined protein and nucleic acid imaging in tissues Page 1 nature
reviewsimmunology https://doi.org/10.1038/s41577-024-01028-2 Research highlights Tools …

The advent of single-cell sequencing technologies has revolutionized cell biology studies.
However, integrative analyses of diverse single-cell data face serious challenges, including …

The re-identification or de-anonymization of users from anonymized data through matching
with publicly available correlated user data has raised privacy concerns, leading to the …