Sepsis, severe sepsis, and septic shock are the increasingly severe stages of the systemic
inflammatory host response to bloodstream infections. The host response to infection is …

Two new commercially available universal rRNA gene PCR plus sequencing tests,
SepsiTest and universal microbe detection (UMD; Molzym, Bremen, Germany), were …

Background Sepsis is triggered by an infection and represents one of the greatest
challenges of modern intensive care medicine. With regard to a targeted antimicrobial …

Infectious disease management essentially consists in identifying the microbial cause (s) of
an infection, initiating if necessary antimicrobial therapy against microbes, and controlling …

The ubiquity and transferability of soil makes it a resource for the forensic investigator, as it
can provide a link between agents and scenes. However, the information contained in soils …

Ixodes pacificus ticks can harbor a wide range of human and animal pathogens. To survey
the prevalence of tick-borne known and putative pathogens, we tested 982 individual adult …

Mortality from bloodstream infections (BSIs) correlates with diagnostic delay and the use of
inappropriate empirical treatment. Early PCR-based diagnosis could decrease inappropriate …

Ixodes ricinus ticks are vectors of numerous human and animal pathogens. They are host
generalists able to feed on more than 300 vertebrate species. The prevalence of tick-borne …

Methods: The Next GeneSiPS-Trial is a prospective, observational, non-interventional,
multicenter study used to assess the diagnostic performance of an NGS-based approach for …

Objective To distinguish between prostaglandin and prostamide concentrations in the
amniotic fluid of women who had an episode of preterm labor with intact membranes …