Polycystic ovary syndrome and oxidative stress—from bench to bedside

N Zeber-Lubecka, M Ciebiera, EE Hennig - International journal of …, 2023 - mdpi.com
Oxidative stress (OS) is a condition that occurs as a result of an imbalance between the
production of reactive oxygen species (ROS) and the body's ability to detoxify and neutralize …

The link between obesity and the skin

R Darlenski, V Mihaylova… - Frontiers in nutrition, 2022 - frontiersin.org
Obesity as a multi-organ disease that affects the entire human organism. Notably, the skin is
no exclusion from this postulate. Skin changes in obese patients have been widely studied …

Deficiency of adipose aryl hydrocarbon receptor protects against diet-induced metabolic dysfunction through sexually dimorphic mechanisms

N Haque, ES Ojo, SL Krager, SA Tischkau - Cells, 2023 - mdpi.com
The molecular mechanisms underlying diet-induced obesity are complex and remain
unclear. The activation of the aryl hydrocarbon receptor (AhR), a xenobiotic sensor, by …

Long‐term health outcomes in young women with polycystic ovary syndrome: a narrative review

LA Allen, N Shrikrishnapalasuriyar… - Clinical …, 2022 - Wiley Online Library
Polycystic ovary syndrome (PCOS) has long been recognized as a common disorder in
young women leading to reproductive and cutaneous sequelae. However, the associated …

Therapeutic exploration of polyherbal formulation against letrozole induced PCOS rats: a mechanistic approach

A Balasubramanian, S Pachiappan, S Mohan… - Heliyon, 2023 - cell.com
Objective This study aimed to develop an effective alternative medicine with multi potential
herbs against polycystic ovarian syndrome (PCOS) in rats induced by letrozole treatment …

Differentiating polycystic ovary syndrome from adrenal disorders

M Yesiladali, MGK Yazici, E Attar, F Kelestimur - Diagnostics, 2022 - mdpi.com
Although polycystic ovary syndrome (PCOS) is primarily considered a hyperandrogenic
disorder in women characterized by hirsutism, menstrual irregularity, and polycystic ovarian …

Acanthosis nigricans: pointer of endocrine entities

AM Radu, M Carsote, MC Dumitrascu, F Sandru - Diagnostics, 2022 - mdpi.com
Acanthosis nigricans (AN) has been reported in relation to insulin resistance (IR). We aim to
review AN through an endocrine and metabolic perspective focusing on IR in association …

Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction

Y Liu, J Jiang, S Du, L Mu, J Fan, J Hu, Y Ye, M Ding… - Science, 2024 - science.org
Polycystic ovary syndrome (PCOS), a prevalent reproductive disorder in women of
reproductive age, features androgen excess, ovulatory dysfunction, and polycystic ovaries …

Genetic variants of Metabolism and Inflammatory pathways, and PCOS risk–Systematic review, Meta-analysis, and In-silico analysis

P Sharma, K Bhatia, HS Kapoor, B Kaur, P Khetarpal - Gene, 2023 - Elsevier
Importance: Identification of genetic risk factors for PCOS susceptibility. Objective To identify
genetic risk variants of the genes involved in metabolic or inflammatory pathways. Data …

The role of inositols in the hyperandrogenic phenotypes of PCOS: A re-reading of Larner's results

V Fedeli, A Catizone, A Querqui, V Unfer… - International Journal of …, 2023 - mdpi.com
Polycystic ovarian syndrome (PCOS) is the most common endocrinological disorder in
women, in which, besides chronic anovulation/oligomenorrhea and ovarian cysts …