Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week

ME Farkouh, GW Stone, A Lala, E Bagiella… - Journal of the American …, 2022 - jacc.org
Clinical, laboratory, and autopsy findings support an association between coronavirus
disease-2019 (COVID-19) and thromboembolic disease. Acute COVID-19 infection is …

Clinical features of thrombosis and bleeding in COVID-19

MR Thomas, M Scully - Blood, The Journal of the American …, 2022 - ashpublications.org
Infection with the SARS-CoV-2 virus, resulting in COVID-19 disease, has presented a
unique scenario associated with high rates of thrombosis. The risk of venous thrombosis is …

Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid …

M Sholzberg, GH Tang, H Rahhal, M AlHamzah… - bmj, 2021 - bmj.com
Objective To evaluate the effects of therapeutic heparin compared with prophylactic heparin
among moderately ill patients with covid-19 admitted to hospital wards. Design Randomised …

Randomized trial of anticoagulation strategies for noncritically ill patients hospitalized with COVID-19

GW Stone, ME Farkouh, A Lala, E Tinuoye… - Journal of the American …, 2023 - jacc.org
Background Prior studies of therapeutic-dose anticoagulation in patients with COVID-19
have reported conflicting results. Objectives We sought to determine the safety and …

Randomized trials of therapeutic heparin for COVID‐19: a meta‐analysis

M Sholzberg, BR da Costa, GH Tang… - … and practice in …, 2021 - Wiley Online Library
Background Pulmonary endothelial injury and microcirculatory thromboses likely contribute
to hypoxemic respiratory failure, the most common cause of death, in patients with COVID …

TEG®, Microclot and Platelet Mapping for Guiding Early Management of Severe COVID-19 Coagulopathy

GJ Laubscher, PJ Lourens, C Venter, DB Kell… - Journal of clinical …, 2021 - mdpi.com
An important component of severe COVID-19 disease is virus-induced endothelilitis. This
leads to disruption of normal endothelial function, initiating a state of failing normal clotting …

Immuno-thrombotic complications of COVID-19: implications for timing of surgery and anticoagulation

CM Bunch, EE Moore, HB Moore, MD Neal… - Frontiers in …, 2022 - frontiersin.org
Early in the coronavirus disease 2019 (COVID-19) pandemic, global governing bodies
prioritized transmissibility-based precautions and hospital capacity as the foundation for …

Anticoagulant Treatment Regimens in Patients With Covid‐19: A Meta‐Analysis

A Jorda, JM Siller‐Matula, M Zeitlinger… - Clinical …, 2022 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) is associated with a hypercoagulable state. It has
been hypothesized that higher‐dose anticoagulation, including therapeutic‐dose and …

COVID-19 coagulopathy: from pathogenesis to treatment

T Alnima, MMG Mulder, BCT van Bussel… - Acta …, 2022 - karger.com
Abstract Coronavirus disease 2019 (COVID-19) has emerged as a pandemic at the end of
2019 and continues to exert an unfavorable worldwide health impact on a large proportion …

Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital: systematic review and network meta-analysis

RJ Eck, T Elling, AJ Sutton, J Wetterslev, C Gluud… - Bmj, 2022 - bmj.com
Objective To assess the benefits and harms of different types and doses of anticoagulant
drugs for the prevention of venous thromboembolism in patients who are acutely ill and …