Biological and functional multimorbidity—from mechanisms to management

C Langenberg, AD Hingorani, CJM Whitty - Nature Medicine, 2023 - nature.com
Globally, the number of people with multiple co-occurring diseases will increase
substantially over the coming decades, with important consequences for patients, carers …

[HTML][HTML] Role of sirtuins in attenuating plaque vulnerability in atherosclerosis

P Velpuri, V Rai, DK Agrawal - Molecular and Cellular Biochemistry, 2024 - Springer
Atherosclerosis is characterized by the development of intimal plaque, thrombosis, and
stenosis of the vessel lumen causing decreased blood flow and hypoxia precipitating …

[HTML][HTML] Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study

B Raman, C McCracken, MP Cassar… - The Lancet …, 2023 - thelancet.com
Introduction The multiorgan impact of moderate to severe coronavirus infections in the post-
acute phase is still poorly understood. We aimed to evaluate the excess burden of …

[HTML][HTML] A comprehensive analysis of all-cause and cause-specific excess deaths in 30 countries during 2020

G Alicandro, C La Vecchia, N Islam… - European Journal of …, 2023 - Springer
The impact of COVID-19 on mortality from specific causes of death remains poorly
understood. This study analysed cause-of-death data provided by the World Health …

[HTML][HTML] Direct and indirect effects of the COVID-19 pandemic on mortality in Switzerland

J Riou, A Hauser, A Fesser, CL Althaus… - Nature …, 2023 - nature.com
The direct and indirect impact of the COVID-19 pandemic on population-level mortality is of
concern to public health but challenging to quantify. Using data for 2011–2019, we applied …

[HTML][HTML] Major cardiovascular events after COVID-19, event rates post-vaccination, antiviral or anti-inflammatory therapy, and temporal trends: rationale and …

B Bikdeli, CD Khairani, D Krishnathasan, A Bejjani… - Thrombosis …, 2023 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19) is associated with excess risk
of cardiovascular and thrombotic events in the early post-infection period and during …

Pneumonia-induced inflammation, resolution and cardiovascular disease: causes, consequences and clinical opportunities

C Stotts, VF Corrales-Medina, KJ Rayner - Circulation Research, 2023 - Am Heart Assoc
Pneumonia is inflammation in the lungs, which is usually caused by an infection. The
symptoms of pneumonia can vary from mild to life-threatening, where severe illness is often …

[HTML][HTML] Role of angiotensin ii in cardiovascular diseases: introducing bisartans as a novel therapy for coronavirus 2019

J Swiderski, LK Gadanec, V Apostolopoulos, GJ Moore… - Biomolecules, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are the main contributors to global morbidity and mortality.
Major pathogenic phenotypes of CVDs include the development of endothelial dysfunction …

[HTML][HTML] Atherosclerosis, cardiovascular disease, and COVID-19: a narrative review

C Vilaplana-Carnerero, M Giner-Soriano, À Dominguez… - Biomedicines, 2023 - mdpi.com
Atherosclerosis is a chronic inflammatory and degenerative process that mainly occurs in
large-and medium-sized arteries and is morphologically characterized by asymmetric focal …

Uncertainties about the Roles of Anticoagulation and Microclots in Post-acute Sequelae of SARS-CoV-2 Infection

JM Connors, RAS Ariëns - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Three years after the start of the pandemic, approaches to the prevention and treatment of
acute Covid-19 have been established. However, post-acute sequelae of SARS-CoV-2 …