Exploring the cardioprotective effects of canagliflozin against cisplatin‐induced cardiotoxicity: Role of iNOS/NF‐κB, Nrf2, and Bax/cytochrome C/Bcl‐2 signals

FEM Ali, EHM Hassanein… - … of Biochemical and …, 2023 - Wiley Online Library
Cardiotoxicity is a severe considerable side effect of cisplatin (CDDP) that requires much
medical attention. The current study investigates the cardioprotective effects of canagliflozin …

Berberis lyceum root bark extract attenuates anticancer drugs induced neurotoxicityand cardiotoxicity in rats

S Qurat-ul-Ain, A Rukhsana, SI Tariq, A Kanwal - African Health Sciences, 2022 - ajol.info
Objective: This study was undertaken to determine in vivo effects of Berberis lyceum root
bark against doxorubicin-induced cardiotoxicity and cisplatin-induced neurotoxicity in …

[图书][B] Acacias: The Genus Acacia (Sensu Lato)

EP Lansky, HM Paavilainen, S Lansky - 2023 - taylorfrancis.com
Acacias: The Genus Acacia (sensu lato) is an evidence-based treatment of this supergenus,
through the eyes of a clinical pharmacognosist and integrative medicine specialist. The book …

The treatment effect of silymarin on heart damage in rats

I Aktas, M Ozgocmen - 2020 - annalsmedres.org
Aim: In this article, we evaluated the possible cardiac protective effects of silymarin on
valproic acid-induced heart injury by histological and biochemical parameters in rat heart …

An integrated view of cisplatin-induced nephrotoxicity, hepatotoxicity, and cardiotoxicity: characteristics, common molecular mechanisms, and current clinical …

CA Oliveira, ÉAB Mercês, FS Portela… - Clinical and …, 2024 - Springer
Cisplatin (CP) is a chemotherapy drug widely prescribed to treat various neoplasms.
Although fundamental for the therapeutic action of the drug, its cytotoxic mechanisms trigger …

Morphine deteriorates cisplatin-induced cardiotoxicity in rats and induces dose-dependent cisplatin chemoresistance in MCF-7 human breast cancer cells

AAK El-Sheikh, Z Khired - Cardiovascular Toxicology, 2021 - Springer
Morphine (MOR) is a strong analgesic that is often used in treatment of severe pains during
cancer treatment, and thus might be concomitantly used with anticancer drugs as cisplatin …

Anticancer Activity of Metallodrugs and Metallizing Host Defense Peptides—Current Developments in Structure-Activity Relationship

CM Curieses Andrés, JM Pérez de Lastra… - 2024 - digital.csic.es
This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …

Silymarin's Potential in Countering Drug-induced Cardiotoxicity, Nephrotoxicity, and Hepatotoxicity: A Narrative Review

A Karimian, L Mahmoudi - Trends in Pharmaceutical Sciences, 2024 - tips.sums.ac.ir
According to availability of natural products, lower cost and less toxic effects compared to
synthetic drugs make them an easy and excellent choice in the treatment of diseases …

[HTML][HTML] P-Glycoprotein/ABCB1 might contribute to morphine/cisplatin-induced hepatotoxicity in rats

AAK El-Sheikh - Scientia Pharmaceutica, 2020 - mdpi.com
To investigate combined effect of the anticancer drug cisplatin (CP) and the opiate analgesic
morphine (MOR) on liver, rats were administered MOR (10 mg/kg/day ip for 10 days), with or …

A Comparative Histological and Immunohistochemical Study on the Possible Therapeutic Effects of Empagliflozin and platelet-rich plasma Against Cisplatin Induced …

AA El-Shafei, RM Hassan… - Egyptian Journal of …, 2023 - ejh.journals.ekb.eg
Introduction and Objectives: Cisplatin is a highly effective chemotherapeutic drug used to
treat various cancers. However, cardiotoxicity is one of the most important adverse effects of …