Bioactive compounds in food as a current therapeutic approach to maintain a healthy intestinal epithelium

E Salinas, D Reyes-Pavón, NG Cortes-Perez… - Microorganisms, 2021 - mdpi.com
The intestinal epithelium serves as an effective barrier against the external environment,
hampering the passage of potentially harmful substances (such as pathogenic microbes) …

Sodium butyrate protects the intestinal barrier by modulating intestinal host defense peptide expression and gut microbiota after a challenge with deoxynivalenol in …

S Wang, C Zhang, J Yang, X Wang, K Wu… - Journal of agricultural …, 2020 - ACS Publications
This study aims to determine whether sodium butyrate (SB) could antagonize
deoxynivalenol (DON)-induced intestinal epithelial dysfunction. In a four-week feeding trial …

Clinical Potential of Anti-inflammatory Effects of Faecalibacterium prausnitzii and Butyrate in Inflammatory Bowel Disease

S Sitkin, J Pokrotnieks - Inflammatory bowel diseases, 2019 - academic.oup.com
We read with great interest the article by Zhou et al., 1 who found that the antiinflammatory
effects of Faecalibacterium prausnitzii in experimental colitis in rodents were mediated …

Микробиом, дисбиоз толстой кишки и воспалительные заболевания кишечника: когда функция важнее таксономии

СИ Ситкин, ТЯ Вахитов… - Альманах клинической …, 2018 - cyberleninka.ru
Измененный микробиом кишечника (дисбиоз) вовлечен в патогенез большинства
неинфекционных заболеваний органов пищеварения–воспалительные заболевания …

[HTML][HTML] Microbiome, gut dysbiosis and inflammatory bowel disease: That moment when the function is more important than taxonomy

SI Sitkin, TY Vakhitov, EV Demyanova - Almanac of clinical medicine, 2018 - almclinmed.ru
The altered gut microbiome (dysbiosis) is involved in the pathogenesis of most non-
infectious gastrointestinal diseases, such as inflammatory bowel disease (IBD), irritable …

Screening of altered metabolites and metabolic pathways in celiac disease using NMR spectroscopy

E Khalkhal, M Rezaei-Tavirani, F Fathi… - BioMed Research …, 2021 - Wiley Online Library
Background. Celiac disease (CeD) is an autoimmune intestinal disorder caused by gluten
protein consumption in genetically predisposed individuals. As biopsy sampling is an …

Oral butyrate modulates the gut microbiota in patients with inflammatory bowel disease, most likely by reversing proinflammatory metabolic reprogramming of …

S Sitkin, T Vakhitov… - Neurogastroenterology & …, 2021 - search.ebscohost.com
We read with interest the article by Facchin et al, 1 who showed that oral sodium butyrate
supplementation increased levels of bacteria able to produce short-chain fatty acids …

How to increase the butyrate-producing capacity of the gut microbiome: do IBD patients really need butyrate replacement and butyrogenic therapy?

S Sitkin, T Vakhitov, J Pokrotnieks - Journal of Crohn's and …, 2018 - academic.oup.com
We read with great interest the paper by Laserna-Mendieta et al. reporting the reduced
butyrate synthesis capacity of the gut microbiome in Crohn's disease [CD] and ulcerative …

Dietary benzoic acid and supplemental enzymes alter fiber-fermenting taxa and metabolites in the cecum of weaned pigs

NE Diether, SL Nam, J Fouhse… - Journal of Animal …, 2022 - academic.oup.com
Inclusion of enzymes and organic acids in pig diets is an important strategy supporting
decreased antibiotic usage in pork production. However, limited knowledge exists about …

Alterations in polyunsaturated fatty acid metabolism and reduced serum eicosadienoic acid level in ulcerative colitis: is there a place for metabolomic fatty acid …

S Sitkin, J Pokrotnieks - Digestive diseases and sciences, 2018 - Springer
We read with great interest the article by Nishiumi et al.[1], which reported altered levels of
some metabolites, including polyunsaturated fatty acids (PUFAs) and lipid mediators, and …