DNA vaccines against COVID-19: Perspectives and challenges

MM Silveira, GMSG Moreira, M Mendonça - Life sciences, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus known
as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is associated …

[HTML][HTML] Approaches towards fighting the COVID‑19 pandemic

SC Tsai, CC Lu, DT Bau, YJ Chiu… - International …, 2021 - spandidos-publications.com
Abstract The coronavirus disease 2019 (COVID‑19) outbreak, which has caused> 46
millions confirmed infections and> 1.2 million coronavirus related deaths, is one of the most …

Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial

C Gabay, P Emery, R Van Vollenhoven, A Dikranian… - The Lancet, 2013 - thelancet.com
Background Roughly a third of patients with rheumatoid arthritis treated with biological
treatments receive them as monotherapy. Tocilizumab—an inhibitor of interleukin 6 receptor …

Unprecedented environmental and energy impacts and challenges of COVID-19 pandemic

A Siddique, A Shahzad, J Lawler, KA Mahmoud… - Environmental …, 2021 - Elsevier
The rapid transmission tendency, severity, and wide geographical spread of newly emerged
novel coronavirus (SARS-CoV-2) in different environmental matrices, including water, air …

Anxiety associated with COVID-19 and concerns about death: Impacts on psychological well-being

WAD Silva, TR de Sampaio Brito, CR Pereira - Personality and Individual …, 2021 - Elsevier
Situations of public calamity, such as that caused by COVID-19 pandemic, strongly impact
mental health, especially among people who feel most anxious about the imminence of …

Older age and frailty are the chief predictors of mortality in COVID-19 patients admitted to an acute medical unit in a secondary care setting-a cohort study

R Chinnadurai, O Ogedengbe, P Agarwal… - BMC geriatrics, 2020 - Springer
Background There is a need for more observational studies across different clinical settings
to better understand the epidemiology of the novel COVID-19 infection. Evidence on clinical …

Fear of COVID-19 for individuals and family members: Indications from the national cross-sectional study of the epicovid19 web-based survey

L Cori, O Curzio, F Adorni, F Prinelli, M Noale… - International journal of …, 2021 - mdpi.com
The study analyzed the association of the fear of contagion for oneself and for family
members (FMs) during the first wave of the COVID-19 pandemic, with demographic and …

An overview of vaccine development for COVID-19

SH Shahcheraghi, J Ayatollahi, AAA Aljabali… - Therapeutic …, 2021 - Taylor & Francis
The COVID-19 pandemic continues to endanger world health and the economy. The
causative SARS-CoV-2 coronavirus has a unique replication system. The end point of the …

Effect of Arbidol (Umifenovir) on COVID-19: a randomized controlled trial

M Nojomi, Z Yassin, H Keyvani, MJ Makiani… - BMC infectious …, 2020 - Springer
Background Treatment of patients with COVID-19 has included supportive care to mainly
relief symptoms of the disease. Although World Health Organization (WHO) has not …

Therapeutic potential of resveratrol in COVID-19-associated hemostatic disorders

R Giordo, A Zinellu, AH Eid, G Pintus - Molecules, 2021 - mdpi.com
Coagulation disorders, endotheliopathy and inflammation are the most common hallmarks
in SARS-CoV-2 infection, largely determining COVID-19's outcome and severity …