For half a century, the human brain was believed to contain about 100 billion neurons and
one trillion glial cells, with a glia: neuron ratio of 10: 1. A new counting method, the isotropic …

It is a widespread notion that the proportion of glial to neuronal cells in the brain increases
with brain size, to the point that glial cells represent “about 90% of all cells in the human …

Background: All living organisms are made of individual and identifiable cells, whose
number, together with their size and type, ultimately defines the structure and functions of an …

Neuroscientists have become used to a number of “facts” about the human brain: It has 100
billion neurons and 10-to 50-fold more glial cells; it is the largest-than-expected for its body …

Cortical folding is a hallmark of many, but not all, mammalian brains. The degree of folding
increases with brain size across mammals, but at different scales between orders and …

It is usually considered that larger brains have larger neurons, which consume more energy
individually, and are therefore accompanied by a larger number of glial cells per neuron …

The large size and complex organization of the human brain makes it unique among primate
brains. In particular, the neocortex constitutes about 80% of the brain, and this cortex is …

Enough species have now been subject to systematic quantitative analysis of the
relationship between the morphology and cellular composition of their brain that patterns …

The call for a paradigm change in toxicology from the United States National Research
Council in 2007 initiates awareness for the invention and use of human‐relevant alternative …

The CNS white matter makes up about half of the human brain, and with advances in human
imaging it is increasingly becoming clear that changes in the white matter play a major role …