Functional genomics in Spiralia
FM Martín-Zamora, BE Davies… - Briefings in …, 2023 - academic.oup.com
Our understanding of the mechanisms that modulate gene expression in animals is strongly
biased by studying a handful of model species that mainly belong to three groups: Insecta …
biased by studying a handful of model species that mainly belong to three groups: Insecta …
Inhibition of ATM kinase rescues planarian regeneration after lethal radiation
DA Shiroor, KT Wang, BD Sanketi, JK Tapper… - EMBO …, 2023 - embopress.org
As stem cells divide, they acquire mutations that can be passed on to daughter cells. To
mitigate potentially deleterious outcomes, cells activate the DNA damage response (DDR) …
mitigate potentially deleterious outcomes, cells activate the DNA damage response (DDR) …
Purification of Planarian Stem Cells Using a Draq5-Based FACS Approach
Planarians are flatworms that have the remarkable ability to regenerate entirely new
animals. This regenerative ability requires abundant adult stem cells called neoblasts, which …
animals. This regenerative ability requires abundant adult stem cells called neoblasts, which …
A comparative analysis of planarian genomes reveals regulatory conservation in the face of rapid structural divergence
The planarian Schmidtea mediterranea can regenerate its entire body from small tissue
fragments and is studied as whole-body regeneration model species. While well-annotated …
fragments and is studied as whole-body regeneration model species. While well-annotated …
Chromatin remodeling protein BPTF regulates transcriptional stability in planarian stem cells
P Verma, A Sanchez Alvarado, EM Duncan - bioRxiv, 2024 - biorxiv.org
Trimethylation of histone H3 lysine 4 (H3K4me3) correlates strongly with gene expression in
many different organisms, yet the question of whether it plays a causal role in transcriptional …
many different organisms, yet the question of whether it plays a causal role in transcriptional …