[HTML][HTML] N-acetylcysteine for prevention and treatment of COVID-19: current state of evidence and future directions

JL Izquierdo-Alonso, S Pérez-Rial, CG Rivera… - Journal of infection and …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes
coronavirus disease 2019 (COVID-19) and can be associated with serious complications …

Involvement of Il-33 in the pathogenesis and prognosis of major respiratory viral infections: future perspectives for personalized therapy

G Murdaca, F Paladin, A Tonacci, M Borro, M Greco… - Biomedicines, 2022 - mdpi.com
Interleukin (IL)-33 is a key cytokine involved in type-2 immunity and allergic airway disease.
At the level of lung epithelial cells, where it is clearly expressed, IL-33 plays an important …

The impact of curcumin on immune response: an immunomodulatory strategy to treat sepsis

A Allegra, G Mirabile, R Ettari, G Pioggia… - International Journal of …, 2022 - mdpi.com
Primary and secondary immunodeficiencies cause an alteration in the immune response
which can increase the rate of infectious diseases and worsened prognoses. They can also …

Immunometabolic Signature during Respiratory Viral Infection: A Potential Target for Host-Directed Therapies

L Menezes dos Reis, MR Berçot, BG Castelucci… - Viruses, 2023 - mdpi.com
RNA viruses are known to induce a wide variety of respiratory tract illnesses, from simple
colds to the latest coronavirus pandemic, causing effects on public health and the economy …

[HTML][HTML] IFNAR (-/-) Mice Constitute a Suitable Animal Model for Epizootic Hemorrhagic Disease Virus Study and Vaccine Evaluation

L Jiménez-Cabello, S Utrilla-Trigo… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Epizootic hemorrhagic disease (EHD), caused by Epizootic hemorrhagic disease virus
(EHDV), is an emerging and severe livestock disease. Recent incursion and distribution of …

Therapeutic potential of 2-methylquinazolin-4 (3H)-one as an antiviral agent against influenza A virus-induced acute lung injury in mice

R Tian, H Zhu, Y Lu, X Shi, P Tu, H Li, H Huang… - Molecules, 2022 - mdpi.com
Qingdai-Mabo (QM), a traditional Chinese herbal formula composed of medicinal herb and
fungus, has been used for treatment of cough and viral pneumonia. However, the underlying …

Advanced virtual screening enables the discovery of a host-targeting and broad-spectrum antiviral agent

G Chilingaryan, R Izmailyan, R Grigoryan, A Shavina… - Antiviral Research, 2023 - Elsevier
We employed an advanced virtual screening (AVS) approach to identify potential inhibitors
of human dihydroorotate dehydrogenase (DHODH), a validated target for development of …

TBC and COVID: an interplay between two infections

G Murdaca, F Paladin, G Mangini, D Tiso… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction In a historical era dominated by the SARS-CoV-2 pandemic, a fact of growing
interest emerges regarding co-infection with Mycobacterium tuberculosis (M. tuberculosis) …

Coronavirus disease 2019 and pityriasis rosea: A review of the immunological connection

F Borgia, F Li Pomi, C Alessandrello… - The Journal of …, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is characterized by the
activation of a cytokine storm derived from an excess release of cytokine (interleukin [IL]‐6 …

Mesenchymal Stem Cells in the Treatment of COVID-19

BC Guo, KH Wu, CY Chen, WY Lin, YJ Chang… - International Journal of …, 2023 - mdpi.com
Since the emergence of the coronavirus disease 2019 (COVID-19) pandemic, many lives
have been tragically lost to severe infections. The COVID-19 impact extends beyond the …