[HTML][HTML] Role of GM-CSF in lung balance and disease

Y Chen, F Li, M Hua, M Liang, C Song - Frontiers in Immunology, 2023 - frontiersin.org
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic growth
factor originally identified as a stimulus that induces the differentiation of bone marrow …

[HTML][HTML] Diverse roles of lung macrophages in the immune response to influenza A virus

H Li, A Wang, Y Zhang, F Wei - Frontiers in Microbiology, 2023 - frontiersin.org
Influenza viruses are one of the major causes of human respiratory infections and the newly
emerging and re-emerging strains of influenza virus are the cause of seasonal epidemics …

[HTML][HTML] Immunotherapy strategies and prospects for acute lung injury: Focus on immune cells and cytokines

W Zhu, Y Zhang, Y Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a disastrous condition,
which can be caused by a wide range of diseases, such as pneumonia, sepsis, traumas …

[HTML][HTML] Drug repurposing for the treatment of COVID-19: Targeting nafamostat to the lungs by a liposomal delivery system

P Reus, H Guthmann, N Uhlig, M Agbaria… - Journal of Controlled …, 2023 - Elsevier
Despite tremendous global efforts since the beginning of the COVID-19 pandemic, still only
a limited number of prophylactic and therapeutic options are available. Although vaccination …

[HTML][HTML] Modulation of alveolar macrophage and mitochondrial fitness by medicinal plant-derived nanovesicles to mitigate acute lung injury and viral pneumonia

L Ye, Y Gao, SWF Mok, W Liao, Y Wang… - Journal of …, 2024 - Springer
Acute lung injury (ALI) is generally caused by severe respiratory infection and characterized
by overexuberant inflammatory responses and inefficient pathogens-containing, the two …

[HTML][HTML] Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian hamsters

JGB Diego, G Singh, S Jangra, K Handrejk… - PLoS …, 2024 - journals.plos.org
Hybrid immunity (vaccination+ natural infection) to SARS-CoV-2 provides superior
protection to re-infection. We performed immune profiling studies during breakthrough …

[HTML][HTML] Inhibiting immunoregulatory amidase NAAA blocks ZIKV maturation in Human Neural Stem Cells

M Lai, V La Rocca, E Iacono, C Filipponi, A De Carli… - Antiviral Research, 2023 - Elsevier
Recent evidence suggests that lipids play a crucial role in viral infections beyond their
traditional functions of supplying envelope and energy, and creating protected niches for …

[HTML][HTML] Early innate cell interactions with Mycobacterium tuberculosis in protection and pathology of tuberculosis

P Sankar, BB Mishra - Frontiers in Immunology, 2023 - frontiersin.org
Tuberculosis (TB) remains a significant global health challenge, claiming the lives of up to
1.5 million individuals annually. TB is caused by the human pathogen Mycobacterium …

[HTML][HTML] Specialized pro-resolving lipid mediators regulate inflammatory macrophages: A paradigm shift from antibiotics to immunotherapy for mitigating COVID-19 …

V Kumar, N Yasmeen, AA Chaudhary… - Frontiers in molecular …, 2023 - frontiersin.org
The most severe clinical manifestations of the horrifying COVID-19 disease, that claimed
millions of lives during the pandemic time, were Acute respiratory distress syndrome …

[HTML][HTML] MAFB shapes human monocyte–derived macrophage response to SARS-CoV-2 and controls severe COVID-19 biomarker expression

M Simón-Fuentes, I Ríos, C Herrero, F Lasala… - JCI insight, 2023 - ncbi.nlm.nih.gov
Monocyte-derived macrophages, the major source of pathogenic macrophages in COVID-
19, are oppositely instructed by macrophage CSF (M-CSF) or granulocyte macrophage CSF …