Noroviruses—the state of the art, nearly fifty years after their initial discovery

LF Ludwig-Begall, A Mauroy, E Thiry - Viruses, 2021 - mdpi.com
Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here,
we provide an overview of notable advances in norovirus research and provide a short …

Advances in norovirus biology

SM Karst, CE Wobus, IG Goodfellow, KY Green… - Cell host & …, 2014 - cell.com
Human noroviruses are a major cause of epidemic and sporadic gastroenteritis worldwide
and can chronically infect immunocompromised patients. Efforts to develop effective …

Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4

N McFadden, D Bailey, G Carrara, A Benson… - PLoS …, 2011 - journals.plos.org
Small RNA viruses have evolved many mechanisms to increase the capacity of their short
genomes. Here we describe the identification and characterization of a novel open reading …

[HTML][HTML] Pathogenesis of noroviruses, emerging RNA viruses

SM Karst - Viruses, 2010 - mdpi.com
Human noroviruses in the family Caliciviridae are a major cause of epidemic gastroenteritis.
They are responsible for at least 95% of viral outbreaks and over 50% of all outbreaks …

IFN-I and IL-22 mediate protective effects of intestinal viral infection

JA Neil, Y Matsuzawa-Ishimoto, E Kernbauer-Hölzl… - Nature …, 2019 - nature.com
Products derived from bacterial members of the gut microbiota evoke immune signalling
pathways of the host that promote immunity and barrier function in the intestine. How …

A single-amino-acid change in murine norovirus NS1/2 is sufficient for colonic tropism and persistence

TJ Nice, DW Strong, BT McCune, CS Pohl… - Journal of …, 2013 - Am Soc Microbiol
Human norovirus (HuNoV) is the major cause of acute nonbacterial gastroenteritis
worldwide but has no clear animal reservoir. HuNoV can persist after the resolution of …

Inactivation of murine norovirus and fecal coliforms by ferrate (VI) in secondary effluent wastewater

K Manoli, R Maffettone, VK Sharma… - Environmental …, 2019 - ACS Publications
Ferrate (VI)(FeVIO42, Fe (VI)) is an emerging oxidant/disinfectant to treat a wide range of
contaminants and microbial pollutants in wastewater. This study describes the inactivation of …

[HTML][HTML] Norovirus encounters in the gut: multifaceted interactions and disease outcomes

E Hassan, MT Baldridge - Mucosal immunology, 2019 - Elsevier
Noroviruses are major causes of gastroenteritis, with epidemic outbreaks occurring
frequently. They are an important global health concern, especially for pediatric and …

Environmentally-triggered contraction of the norovirus virion determines diarrheagenic potential

EW Helm, AM Peiper, M Phillips, CG Williams… - Frontiers in …, 2022 - frontiersin.org
Noroviruses are the leading cause of severe childhood diarrhea and foodborne disease
worldwide. While they are a major cause of disease in all age groups, infections in the very …

Protruding Domain of Capsid Protein Is Necessary and Sufficient To Determine Murine Norovirus Replication and Pathogenesis In Vivo

DW Strong, LB Thackray, TJ Smith, HW Virgin - Journal of virology, 2012 - Am Soc Microbiol
Human noroviruses (HuNoVs) are the major cause of epidemic, nonbacterial gastroenteritis
worldwide. Due to the lack of a tractable model system and the inability to grow HuNoVs in …