Revealing the biological mechanism of acupuncture in alleviating excessive inflammatory responses and organ damage in sepsis: a systematic review

L Yang, D Zhou, J Cao, F Shi, J Zeng, S Zhang… - Frontiers in …, 2023 - frontiersin.org
Sepsis is a systemic inflammation caused by a maladjusted host response to infection. In
severe cases, it can cause multiple organ dysfunction syndrome (MODS) and even …

[HTML][HTML] Acute respiratory distress syndrome heterogeneity and the septic ARDS subgroup

H Xu, S Sheng, W Luo, X Xu, Z Zhang - Frontiers in Immunology, 2023 - frontiersin.org
Acute respiratory distress syndrome (ARDS) is an acute diffuse inflammatory lung injury
characterized by the damage of alveolar epithelial cells and pulmonary capillary endothelial …

Echinacea polyphenols inhibit NLRP3-dependent Pyroptosis, apoptosis, and necroptosis via suppressing NO production during lipopolysaccharide-induced acute …

J Guo, Y Luo, J Zuo, J Teng, B Shen… - Journal of Agricultural …, 2023 - ACS Publications
PANoptosis is an intricate programmed death pathway that involves the interaction between
pyroptosis, apoptosis, and necroptosis. We systematically explored the protective effect of …

Melatonin attenuates sepsis-induced acute lung injury via inhibiting excessive mitophagy

J Ling, S Yu, F Xiong, T Xu, S Li - Drug Design, Development and …, 2023 - Taylor & Francis
Background Epidemiological studies have indicated that lung injury is a frequent
complication of sepsis. Mitophagy is vital to multiple pathological processes and diseases; …

Endothelial cell dynamics in sepsis-induced acute lung injury and acute respiratory distress syndrome: pathogenesis and therapeutic implications

X Qiao, J Yin, Z Zheng, L Li, X Feng - Cell Communication and Signaling, 2024 - Springer
Sepsis, a prevalent critical condition in clinics, continues to be the leading cause of death
from infections and a global healthcare issue. Among the organs susceptible to the harmful …

Bioinformatics and system biology approach to identify the influences among COVID-19, ARDS and sepsis

P Li, T Li, Z Zhang, X Dai, B Zeng, Z Li, Z Li - Frontiers in Immunology, 2023 - frontiersin.org
Background Severe coronavirus disease 2019 (COVID-19) has led to severe pneumonia or
acute respiratory distress syndrome (ARDS) worldwide. we have noted that many critically ill …

[HTML][HTML] Mefunidone ameliorates lipopolysaccharide-induced acute lung injury through inhibiting MAPK signaling pathway and enhancing Nrf2 pathway

TT Yao, Y Zhang, RL He, X Lv, YJ He, MY Li… - International …, 2022 - Elsevier
Abstract Background and Objective Acute lung injury (ALI) is a life-threatening disease
which has high mortality and lacks effective pharmacological treatments. Excessive …

Monotropein alleviates sepsis-elicited acute lung injury via the NF-κB pathway

Y Gong, J Wang - Journal of Pharmacy and Pharmacology, 2023 - academic.oup.com
Objectives To address the effect and mechanism of Monotropein (Mon) on sepsis-induced
acute lung injury (ALI). Methods ALI model was established by lipopolysaccharide (LPS) …

PROMOTING MITOCHONDRIAL DYNAMIC EQUILIBRIUM ATTENUATES SEPSIS-INDUCED ACUTE LUNG INJURY BY INHIBITING PROINFLAMMATORY …

M Sun, Z Zeng, G Xu, S An, Z Deng, R Cheng, Y Yao… - Shock, 2023 - journals.lww.com
Sepsis-induced acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is
characterized by widespread pulmonary inflammation and immune response, in which …

Liensinine reduces acute lung injury brought on by lipopolysaccharide by inhibiting the activation of the NF-κB signaling pathway through modification of the Src …

H Chen, F Liu, D Dai, Y Ming, Y Xu, Z Huang… - …, 2024 - Springer
ALI is characterized by macrophage-driven inflammation, causing severe lung damage.
Currently, there are limited therapeutic options available for ALI. Liensinine (LIEN), with …