Normal aging is associated with cognitive decline and underlying brain dysfunction.
Previous studies concentrated less on brain network changes at a systems level. Our goal …

Preserved cognitive performance is a key feature of successful aging. Several theoretical
models have been proposed to explain the putative underlying relationship between brain …

Episodic memory declines with older age, but it is unresolved whether this decline reflects
reduced probability of successfully retrieving information from memory, or decreased …

Healthy aging is associated with declines in episodic memory. This reduction is thought to
be due in part to age-related differences in encoding-related processes. In the current study …

In humans, heterogeneity in the decline of hippocampal-dependent episodic memory is
observed during aging. Rodents have been employed as models of age-related cognitive …

This functional magnetic resonance imaging study investigated the relationship between the
neural correlates of associative memory encoding, callosal integrity, and memory …

The present functional magnetic resonance imaging (fMRI) study investigated whether age-
related differences in the neural correlates of successful memory encoding are modulated …

In this study we used functional magnetic resonance imaging to investigate age-related
changes in large-scale brain functional networks during memory encoding and recognition …

To investigate early effects of beta-amyloid (Aβ) on neuronal function, elderly normal
controls (NCs, age range 58–97) were scanned with Pittsburgh Compound-B (PIB) positron …

Neurodegenerative brain changes can affect the functional connectivity strength between
nodes of the default-mode network (DMN), which may underlie changes in cognitive …