Pachyonychia congenita (PC) is characterized by hypertrophic nail dystrophy, painful
palmoplantar keratoderma and blistering, oral leukokeratosis, pilosebaceous cysts …

Few reports are found in the literature regarding the role of planar cell polarity (PCP) in
supporting spermatogenesis in the testis. Yet morphological studies reported decades …

ABSTRACT The Hungarian White Goose (Anser anser domesticus) is an excellent
European goose breed, with high feather and meat production. Despite its importance in the …

Abstract Background The CRISPR/Cas9 system is widely used for genome editing in
human, rat and mouse cells. In this study, we established Fzd6 mutant mice using …

Pachyonychia congenita (PC) is a rare, autosomal dominant inherited disorder of
keratinization that is characterized by a triad of focal palmoplantar keratoderma, plantar …

This report describes a patient with a novel homozygous nonsense variant, nail dysplasia
and diabetes. Only a few patients have been described with FZD6 mutations and nail …

Background Autosomal recessive nail dysplasia is characterized by thick and hard nails with
a very slow growth on the hands and feet. Mutations in FZD6 gene were found to be …

Background: Trachyonychia is a benign nail condition, most commonly seen in children.
Trachyonychia manifests as excessive longitudinal ridging, nail roughness, and nail …

Background Nail disorder nonsyndromic congenital (NDNC) is a very rare clinically and
genetically heterogeneous disease inherited both in recessive or dominant modes. FZD6 is …

Congenital Nail abnormalities are rare ectodermal defects. Autosomal recessive nail
dysplasia is much rarer. Recently it has been recognized as a condition resulting in nail …