The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors

N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …

Natural compounds lower uric acid levels and hyperuricemia: Molecular mechanisms and prospective

S Feng, S Wu, F Xie, CS Yang, P Shao - Trends in Food Science & …, 2022 - Elsevier
Background With the change of dietary habits and lifestyles, people tend to have elevated
blood uric acid levels at a younger age, and this can cause serious health problems, such as …

The prevalence of hyperuricemia and its correlates among adults in China: results from CNHS 2015–2017

W Piao, L Zhao, Y Yang, H Fang, L Ju, S Cai, D Yu - Nutrients, 2022 - mdpi.com
This study aimed to investigate the prevalence of hyperuricemia (HUA) and associated risk
factors in Chinese adults aged 18 to 59 years. All the data were collected from the China …

Uric acid and plant-based nutrition

B Jakše, B Jakše, M Pajek, J Pajek - Nutrients, 2019 - mdpi.com
Plant-based diets (PBDs) are associated with decreased risk of morbidity and mortality
associated with important noncommunicable chronic diseases. Similar to animal-based food …

Uric Acid in Parkinson′ s disease: what is the connection?

F Seifar, AR Dinasarapu, HA Jinnah - Movement Disorders, 2022 - Wiley Online Library
Numerous studies have linked Parkinson′ s disease (PD) with low levels of uric acid (UA).
Low UA has been associated with the risk of developing PD, and its progression and …

Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance

S Lim, SY Ahn, IC Song, MH Chung, HC Jang, KS Park… - PloS one, 2009 - journals.plos.org
There is an apparent overlap between areas in the USA where the herbicide, atrazine (ATZ),
is heavily used and obesity-prevalence maps of people with a BMI over 30. Given that …

[HTML][HTML] The health effects of soy: A reference guide for health professionals

M Messina, A Duncan, V Messina, H Lynch, J Kiel… - Frontiers in …, 2022 - frontiersin.org
Soy is a hotly debated and widely discussed topic in the field of nutrition. However, health
practitioners may be ill-equipped to counsel clients and patients about the use of soyfoods …

Uric acid extrarenal excretion: the gut microbiome as an evident yet understated factor in gout development

EO Méndez-Salazar, GA Martínez-Nava - Rheumatology International, 2022 - Springer
Humans do not produce uricase, an enzyme responsible for degrading uric acid. However,
some bacteria residing in the gut can degrade one-third of the dietary and endogenous uric …

[HTML][HTML] Global, regional, and national prevalence of gout from 1990 to 2019: age-period-cohort analysis with future burden prediction

Q He, TN Mok, TH Sin, J Yin, S Li, Y Yin… - JMIR Public Health …, 2023 - publichealth.jmir.org
Background: Gout is a common and debilitating condition that is associated with significant
morbidity and mortality. Despite advances in medical treatment, the global burden of gout …

Exploring the multifaceted nexus of uric acid and health: a review of recent studies on diverse diseases

M Kuwabara, T Fukuuchi, Y Aoki, E Mizuta, M Ouchi… - Biomolecules, 2023 - mdpi.com
The prevalence of patients with hyperuricemia or gout is increasing worldwide.
Hyperuricemia and gout are primarily attributed to genetic factors, along with lifestyle factors …