Background The correlation between human gut microbiota and psychiatric diseases has
long been recognized. Based on the heritability of the microbiome, genome-wide …

Objective: Postpartum depression (PPD) is a common subtype of major depressive disorder
(MDD) that is more heritable, yet is understudied in psychiatric genetics. The authors …

We conducted a two-sample Mendelian randomization study to determine the association of
smoking initiation with seven psychiatric disorders. We used 353 independent single …

There is a long-standing interest in exploring the relationship between blood-based
biomarkers and psychiatric disorders, despite their causal role being difficult to resolve in …

Background Recent genome-wide association studies (GWASs) have revealed the
polygenic nature of psychiatric disorders and discovered a few of single-nucleotide …

Importance Posttraumatic stress disorder (PTSD) has been reported to be a risk factor for
several physical and somatic symptoms. However, the genetics of PTSD and its potential …

Exposure to stressful life events increases the risk for psychiatric disorders. Mechanistic
insight into the genetic factors moderating the impact of stress can increase our …

Patients exposed to trauma often experience high rates of adverse post-traumatic
neuropsychiatric sequelae (APNS). The biological mechanisms promoting APNS are …

Tinnitus is a heritable, highly prevalent auditory disorder treated by multiple medical
specialties. Previous GWAS indicated high genetic correlations between tinnitus and …

Polygenic risk scores (PRSs) have become an increasingly popular approach for
demonstrating polygenic influences on complex traits and for establishing common …