Leprosy (Hansen's) is a disease caused by Mycobacterium leprae. This disease slowly
leads to occurrence of leprae reactions which mainly damage peripheral nervous system …

The paper is devoted to the recent works on reaction–diffusion models of virus infection
dynamics in human and animal organisms. Various regimes of infection propagation in …

This paper provides a novel perspective in the Protein Structure Prediction (PSP) problem.
The PSP problem focuses on determining putative 3D structures of a protein starting from its …

In the last few years there has been an increasing interest in mathematical and
computational modelling of the human immune system (HIS). Computational models of the …

The innate immune system is the first line of defense against pathogens. Its composition
includes barriers, mucus, and other substances as well as phagocytic and other cells. The …

Many chemical and biological systems involve reacting species with vastly different numbers
of molecules/agents. Hybrid simulations model such phenomena by combining discrete (eg …

Immune checkpoint inhibitors (ICIs), as a novel immunotherapy, are designed to modulate
the immune system to attack malignancies. Despite their promising benefits, immune-related …

In this paper, we present a mathematical model of the immune response to parasites. The
model is a type of predator-prey system in which the parasite serves as the prey and the …

A reaction–diffusion system with two delays, which describes viral infection spreading in the
lymphoid tissue, is investigated. The delays promote very complex dynamics of the model …

The immune system is highly complex system with large number of macromolecules,
signaling pathways, protein-protein interactions, and gene expressions. Studies from …