Central nervous system (CNS) disorders affect as many as 1.5 billion people globally. The
limited delivery of most imaging and therapeutic agents into the brain is a major challenge …

While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

Neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and
Huntington's disease, present a major health issue and financial burden for health care …

Oxidative stress caused by an imbalanced metabolism and an excess of reactive oxygen
species (ROS) lead to a range of health disorders in humans. Our endogenous antioxidant …

As naturally occurring bioactive products, several lines of evidence have shown the potential
of polyphenols in the medical intervention of various diseases, including tumors …

Reactive oxygen species (ROS), highly reactive molecules, are produced by living
organisms as a result ofnormal cellular metabolism and environmental factors, and can …

The oxidation of bioorganic materials by air and, particularly, the oxidative stress involved in
the cell loss and other pathologies associated with neurodegenerative diseases (NDs) are …

Seven ligands bind to and activate the mammalian epidermal growth factor (EGF) receptor
(EGFR/ERBB1/HER1): EGF, transforming growth factor-alpha (TGFA), heparin-binding EGF …

Neuronal dysfunction initiates several intracellular signaling cascades to release different
proinflammatory cytokines and chemokines, as well as various reactive oxygen species. In …

Abstract Mulberry (Morus spp.) of Moraceae family is regarded as a unique plant on this
earth due to its broader geological distribution across the continents; ability to be cultivated …