In animals, systemic control of metabolism is conducted by metabolic tissues and relies on
the regulated circulation of a plethora of molecules, such as hormones and lipoprotein …

Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …

Foam cells play a vital role in the initiation and development of atherosclerosis. This review
aims to summarize the novel insights into the origins, consequences, and molecular …

Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

Atherosclerosis is one of the most fatal diseases in the world. The associated thickening of
the arterial wall and its background and consequences make it a very composite disease …

The gut microbiota plays an important role in controlling atherosclerosis progression to
support the link between the gut and coronary heart disease. Recent studies have shown …

Background: miRNA therapeutics have gained attention during the past decade. These
oligonucleotide treatments can modulate the expression of miRNAs in vivo and could be …

Congenital myasthenia (CM) is a devastating neuromuscular disease, and mutations in
DOK7, an adaptor protein that is crucial for forming and maintaining neuromuscular …

Macrophages are crucial in the progression of atherosclerotic cardiovascular disease
(ASCVD). In the atherosclerotic lesions, macrophages play a central role in maintaining …

Celastrol is a triterpene derived from the traditional Chinese medicine Tripterygium wilfordii
Hook f, which displays potential anticancer activity. In the present study, we investigated the …